Evidence map›Paper›PMID 36531808›Full record

ArticleIranian journal of microbiology2022

Reviving the role of mecillinam against extended spectrum beta-lactamase producing enterobacterales.

Fatima Kaleem, Irum Aftab, Umme Farwa, Hassan Saleem, Saima Ishtiaq, Saima Syed, Shahid Ahmad Abbasi

Open access · diamondAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fatima KaleemDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Irum AftabDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Umme FarwaDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Hassan SaleemDepartment of Surgery, Quaid I Azam International Hospital, Islamabad, Pakistan.
Saima IshtiaqDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Saima SyedDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Shahid Ahmad AbbasiDepartment of Pathology, Foundation University Medical College, FUI, Islamabad, Pakistan.
Foundation University Medical College · PKQuaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: This study was designed to determine the Materials and Methods: After proper permission from Ethical Review Committee of the Institute, all samples yielding growth of ESBL producing Enterobacterales were part of the study and were processed according to routine microbiological procedures. Routine antibiotic sensitivity testing was done on Muller Hinton Agar by Modified Kirby Bauer Method. All Gram negative isolates were subjected to concomitant detection of ESBL production by double disc synergy method. All ESBL producers were then subjected to the mecillinam Minimum Inhibitory Concentration (MIC) determination by E test. The results were interpreted as per CLSI Guidelines. Results: A total of 120 ESBL producing Enterobacterales isolates were included in the study. The mean age of patients with ESBL infection was 45 ± 18.7 years. There were 44% male and 55% female patients. Majority of the ESBL producing Enterobacterales were isolated from urine samples (56%), followed by pus. Among the isolated organisms, Conclusion: Mecillinam shows good

Indexed as

Extended spectrum β-lactamaseIn vitro susceptibility

Identifiers

PMID36531808
PMCPMC9723427
OpenAlexW4307243762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.