Evidence map›Paper›PMID 36531804›Full record

ArticleJournal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B2023

High sensitivity CIP2A detection for oral cancer using a rapid transistor-based biosensor module.

Minghan Xian, Jenna L Stephany, Chan-Wen Chiu, Chao-Ching Chiang, Fan Ren, Cheng-Tse Tsai, Siang-Sin Shan, Yu-Te Liao, Josephine F Esquivel-Upshaw, Stephen J Pearton

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. High sensitivity saliva-based biosensor in detection of breast cancer biomarkers: HER2 and CA15-3.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Minghan XianDepartment of Chemical Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0002-6854-7569
Jenna L StephanyDepartment of Restorative Dental Sciences, University of Florida, Gainesville, Florida 32610.
Chan-Wen ChiuDepartment of Chemical Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0002-7499-0006
Chao-Ching ChiangDepartment of Chemical Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0002-0447-8170
Fan RenDepartment of Chemical Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0001-9234-019X
Cheng-Tse TsaiDepartment of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Siang-Sin ShanDepartment of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Yu-Te LiaoDepartment of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Josephine F Esquivel-UpshawDepartment of Restorative Dental Sciences, University of Florida, Gainesville, Florida 32610.
Stephen J PeartonDepartment of Materials Science and Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0001-6498-1256
University of Florida · USNational Yang Ming Chiao Tung University · TW

Funding

Novel coatings to minimize surface degradation and fracture susceptibility of dental ceramicsR01DE025001 · NIDCR · UNIVERSITY OF FLORIDA · PI ESQUIVEL-UPSHAW, JOSEPHINE F. · 2016 to 2020
$4.2M
Novel coated nanostructured implant surfaces to increase osseointegration and decrease peri-implantitis in a physiologic rat modelR56DE025001 · NIDCR · UNIVERSITY OF FLORIDA · PI ESQUIVEL-UPSHAW, JOSEPHINE F. · 2022 to 2022
$650k
NIDCR NIH HHS R01 DE025001NIDCR NIH HHS R56 DE025001
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is one of the most common lip and oral cavity cancer types. It requires early detection via various medical technologies to improve the survival rate. While most detection techniques for OSCC require testing in a centralized lab to confirm cancer type, a point of care detection technique is preferred for on-site use and quick result readout. The modular biological sensor utilizing transistor-based technology has been leveraged for testing CIP2A, and optimal transistor gate voltage and load resistance for sensing setup was investigated. Sensitivities of 1 × 10

Identifiers

PMID36531804
PMCPMC9750712
OpenAlexW4311312975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.