Evidence map›Paper›PMID 36531515›Full record

ArticleJournal of frailty, sarcopenia and falls2022

Association of Obesity with Cognitive Impairment and Depression among Oldest Old Population having Frailty syndrome.

Gunampalli Anaika, Sai Sruthi Regalla, Bana Manishaa Reddy, Enakshi Ganguly, Pawan Kumar Sharma

Abstract read
In one paragraph

Article in Journal of frailty, sarcopenia and falls, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gunampalli AnaikaMediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.
Sai Sruthi RegallaMediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.
Bana Manishaa ReddyMediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.
Enakshi GangulyEpidemiology, Department of Community Medicine, Mediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.
Pawan Kumar SharmaEpidemiology, Department of Community Medicine, Mediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.

Funding

SHARE India University Pittsburgh Population and Intervention Research TrainingD43TW009078 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUNKER, CLAREANN H. · 2011 to 2015
$1.0M
FIC NIH HHS D43 TW009078
6 · The paper itself

Abstract

Objectives: The objectives were to estimate prevalence of obesity among frail individuals aged ≥80 years and examine the association of obesity with cognitive impairment and depression among frail individuals aged ≥80 years. Methods: Two-hundred community-dwelling participants aged ≥80 years, were enrolled; 166 frail participants were further analyzed. Obesity and adiposity were determined by Body Mass Index (BMI), Waist Circumference (WC) and Body Fat Percentage (BF%). Cognitive impairment and Depression were assessed using Mini Mental State Examination (MMSE) and Geriatric Depression Scale (GDS-15). Frailty was assessed by Fried criteria. Chi-Square, t-test, trend-analysis and Logistic Regression (LR) were done. Results: Obesity among Frail individuals aged ≥80 years was 40% using BMI and 73.2% using WC. Obesity was inversely associated with cognitive impairment and depression among frail individuals. Severity of cognitive impairment and depression was lower among obese frail than non-obese frail. Trend-analysis showed decreasing cognitive impairment and depression with increasing BF%. On LR, obesity among frail individuals had inverse association with cognitive impairment and depression. Conclusion: Obesity among frail individuals aged ≥80 years was associated with lower odds of cognitive impairment and depression in our population. Positive effects of weight gain in oldest old frail individuals and development of cognitive impairment and dementia should be explored in further researches.

Indexed as

Cognitive ImpairmentDepressionElderlyFrailtyObesity

Identifiers

PMID36531515
PMCPMC9729753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.