Evidence map›Paper›PMID 36531327›Full record

ArticleFrontiers in chemistry2022

Mesoporous nanoplatform integrating photothermal effect and enhanced drug delivery to treat breast cancer bone metastasis.

Wujun Miao, Yunfan Ti, Jingwei Lu, Jianning Zhao, Bin Xu, Liang Chen, Nirong Bao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wujun MiaoDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Yunfan TiDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Jingwei LuDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Jianning ZhaoDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Bin XuDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Liang ChenMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai, China.
Nirong BaoDepartment of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Nanjing General Hospital of Nanjing Military Command · CNNanjing University · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastatic breast cancer has severely threatened the survival and life quality of patients. Due to the suboptimal efficacy of anti-metastatic chemotherapeutic drugs and the complicated bone marrow microenvironments, effective treatment of metastatic breast cancer remains challenging for traditional clinical approaches. In this work, we developed a mesoporous nanoplatform (m-CuS-PEG) with the co-loading of CuS nanodots and a chemotherapeutic drug cisplatin for the combined photothermal-chemotherapy of bone-metastasized breast cancer. The CuS nanodots were decorated onto mesoporous silica (m-SiO

Indexed as

bone metastasisbreast cancerdrug deliverymesoporous nanoplatformphotothermal therapy

Identifiers

PMID36531327
PMCPMC9749821
OpenAlexW4310992440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.