Evidence map›Paper›PMID 36531127›Full record

ArticleMacromolecular materials and engineering2022

Extracellular Matrix Microparticles Improve GelMA Bioink Resolution for 3D Bioprinting at Ambient Temperature.

Zachary Galliger, Caleb D Vogt, Haylie R Helms, Angela Panoskaltsis-Mortari

Open access · hybridAbstract read
In one paragraph

Article in Macromolecular materials and engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zachary GalligerBiomedical Engineering Graduate Program, University of Minnesota, Minneapolis, MN.
Caleb D VogtBiomedical Engineering Graduate Program; Medical Scientist Training Program, University of Minnesota, 420 Delaware St. SE, Minneapolis, MN.
Haylie R HelmsDepartment of Pediatrics, Division of Blood and Marrow Transplantation & Cell Therapy, University of Minnesota, 420 Delaware St. SE, Minneapolis, MN.
Angela Panoskaltsis-MortariDepartment of Pediatrics, Division of Blood and Marrow Transplantation & Cell Therapy; Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep, University of Minnesota, 420 Delaware St. SE., Minneapolis, MN.
University of Minnesota · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
TRAINING-PULMONARY CELL &MOLECULAR BIOLOGY &PHYSIOLOGYT32HL007741 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUDLEY, R. ADAMS, INGBAR, DAVID H · 1994 to 2023
$13.9M
3D Bioprinting for Tracheal ReconstructionF31HL142313 · NHLBI · UNIVERSITY OF MINNESOTA · PI GALLIGER, ZACHARY · 2018 to 2020
$135k
NCATS NIH HHS UL1 TR002494NHLBI NIH HHS F31 HL142313NHLBI NIH HHS T32 HL007741
6 · The paper itself

Abstract

Introduction: Current bioinks for 3D bioprinting, such as gelatin-methacryloyl, are generally low viscosity fluids at room temperature, requiring specialized systems to create complex geometries. Methods and Results: Adding decellularized extracellular matrix microparticles derived from porcine tracheal cartilage to gelatin-methacryloyl creates a yield stress fluid capable of forming self-supporting structures. This bioink blend performs similarly at 25°C to gelatin-methacryloyl alone at 15°C in linear resolution, print fidelity, and tensile mechanics. Conclusion: This method lowers barriers to manufacturing complex tissue geometries and removes the need for cooling systems.

Indexed as

3D bioprintingextracellular matrixhydrogellarynxtissue engineeringtrachea

Identifiers

PMID36531127
PMCPMC9757590
OpenAlexW4286489803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.