ArticleFrontiers in oncology2022
Multi-modality radiomics nomogram based on DCE-MRI and ultrasound images for benign and malignant breast lesion classification.
Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Performance of artificial intelligence-assisted ultrasound elastography in classifying benign and malignant breast tumors: a systematic review and meta-analysis.BMC medical imaging · 2025Pooled it
- Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026Article
- Nomogram for reducing unnecessary biopsies of breast lesions based on MRI and clinical features: a multi-center retrospective cohort study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Article
- A deep learning model to enhance the classification of primary bone tumors based on incomplete multimodal images in X-ray, CT, and MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Intelligent scoring system based on dynamic optical breast imaging for early detection of breast cancer.Biomedical optics express · 2024Article
- Freehand 1.5T MR-Guided Vacuum-Assisted Breast Biopsy (MR-VABB): Contribution of Radiomics to the Differentiation of Benign and Malignant Lesions.Diagnostics (Basel, Switzerland) · 2023Article
- A clinical-radiomics nomogram based on multimodal ultrasound for predicting the malignancy risk in solid hypoechoic breast lesions.Frontiers in oncology · 2023Article
- A Comprehensive Model Based on Dynamic Contrast-Enhanced Magnetic Resonance Imaging Can Better Predict the Preoperative Histological Grade of Breast Cancer Than a Radiomics Model.Breast cancer (Dove Medical Press) · 2023Article
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Abstract
Objective: To develop a multi-modality radiomics nomogram based on DCE-MRI, B-mode ultrasound (BMUS) and strain elastography (SE) images for classifying benign and malignant breast lesions. Material and Methods: In this retrospective study, 345 breast lesions from 305 patients who underwent DCE-MRI, BMUS and SE examinations were randomly divided into training (n = 241) and testing (n = 104) datasets. Radiomics features were extracted from manually contoured images. The inter-class correlation coefficient (ICC), Mann-Whitney U test and the least absolute shrinkage and selection operator (LASSO) regression were applied for feature selection and radiomics signature building. Multivariable logistic regression was used to develop a radiomics nomogram incorporating radiomics signature and clinical factors. The performance of the radiomics nomogram was evaluated by its discrimination, calibration, and clinical usefulness and was compared with BI-RADS classification evaluated by a senior breast radiologist. Results: The All-Combination radiomics signature derived from the combination of DCE-MRI, BMUS and SE images showed better diagnostic performance than signatures derived from single modality alone, with area under the curves (AUCs) of 0.953 and 0.941 in training and testing datasets, respectively. The multi-modality radiomics nomogram incorporating the All-Combination radiomics signature and age showed excellent discrimination with the highest AUCs of 0.964 and 0.951 in two datasets, respectively, which outperformed all single modality radiomics signatures and BI-RADS classification. Furthermore, the specificity of radiomics nomogram was significantly higher than BI-RADS classification (both Conclusion: The proposed multi-modality radiomics nomogram based on DCE-MRI and ultrasound images has the potential to serve as a non-invasive tool for classifying benign and malignant breast lesions and reduce unnecessary biopsy.
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