Evidence map›Paper›PMID 36530989›Full record

SynthesisFrontiers in oncology2022

Prognostic value of Musashi 2 (MSI2) in cancer patients: A systematic review and meta-analysis.

Lin Jiang, Shanshan Xue, Jie Xu, Xiaoyang Fu, Jing Wei, Chuanmeng Zhang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lin JiangDepartment of Anesthesiology, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Shanshan XueDepartment of Clinical Laboratory, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Jie XuThe Center for Translational Medicine, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Xiaoyang FuThe Center for Translational Medicine, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Jing WeiDepartment of Obstetrics and Gynecology, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Chuanmeng ZhangThe Center for Translational Medicine, Taizhou People's Hospital, Affiliated to Nanjing Medical University, Taizhou, Jiangsu, China.
Nanjing Medical University · CNNantong University · CNTaizhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Musashi 2 (MSI2) is an RNA-binding protein that regulates mRNA translation of numerous intracellular targets and plays an important role in the development of cancer. However, the prognostic value of MSI2 in various cancers remains controversial. Herein, we conducted this meta-analysis including 21 studies with 2640 patients searched from PubMed, Web of Science, EMBASE, Chinese National Knowledge Infrastructure databases, and WanFang databases to accurately assess the prognostic significance of MSI2 in various cancers. Our results indicated that high MSI2 expression was significantly related to poor overall survival (HR = 1.84, 95% CI: 1.66-2.05,

Indexed as

cancerclinicopathological featuresmeta-analysisMSI2prognosis

Identifiers

PMID36530989
PMCPMC9751961
OpenAlexW4310500760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.