Evidence map›Paper›PMID 36530956›Full record

Observational studyCardiovascular therapeutics2022

Safety and Efficacy of Bivalirudin versus Unfractionated Heparin Monotherapy in Patients with CAD and DM Undergoing PCI: A Retrospective Observational Study.

Jing Li, Sanbao Chen, Sicong Ma, Mingque Yang, Zizhao Qi, Kun Na, Miaohan Qiu, Yi Li, Yaling Han

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Cardiovascular therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jing LiThe Graduate School of Harbin Medical University, Harbin, China.ORCID https://orcid.org/0000-0002-4912-5977
Sanbao ChenDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0003-1279-0559
Sicong MaDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0002-2233-9967
Mingque YangDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0002-3253-183X
Zizhao QiDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0003-4427-4399
Kun NaDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0003-3679-8248
Miaohan QiuDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0003-2077-5770
Yi LiDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang, Liaoning Province, China.ORCID https://orcid.org/0000-0003-1658-404X
Yaling HanThe Graduate School of Harbin Medical University, Harbin, China.ORCID https://orcid.org/0000-0003-4569-6737
General Hospital of Shenyang Military Region · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Optimal anticoagulants for patients with diabetes mellitus (DM) undergoing percutaneous coronary intervention (PCI) are unclear. This retrospective observational study is aimed at evaluating efficacy and safety of bivalirudin versus unfractionated heparin (UFH) monotherapy in patients with DM undergoing PCI. Methods: A total of 3890 diabetic patients receiving PCI in the General Hospital of Northern Theater Command were divided into the bivalirudin group ( Results: After propensity score matching, the bivalirudin group was associated with a lower incidence of NACEs (3.0% vs. 6.0%, Conclusion: In diabetic patients undergoing PCI, bivalirudin was significantly associated with reduced risks of 30-day NACE and MACCE, mainly driven by the lower rates of bleeding and mortality, compared with heparin monotherapy.

Indexed as

Diabetes MellitusPercutaneous Coronary InterventionAnticoagulantsAntithrombinsFibrinolytic AgentsHemorrhageHeparinHirudinsHumansPeptide FragmentsRecombinant ProteinsTreatment OutcomeAnticoagulantsAntithrombinsbivalirudinFibrinolytic AgentsHeparinHirudinsPeptide FragmentsRecombinant Proteins

Identifiers

PMID36530956
PMCPMC9729030
OpenAlexW4310735878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.