Evidence map›Paper›PMID 36530918›Full record

ArticleFrontiers in medicine2022

Back to basics with newer technology: Should we focus on reducing work of breathing earlier?

Christopher Sciarretta, Jeremy Greenberg, Kara D Wyatt, Jessica S Whittle

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher SciarrettaDepartment of Emergency Medicine, University of Tennessee College of Medicine, Chattanooga, TN, United States.
Jeremy GreenbergDepartment of Respiratory, Critical Care, and Sleep Medicine, University of Tennessee, Chattanooga/Erlanger Health, Chattanooga, TN, United States.
Kara D WyattScientific Consultant, Chattanooga, TN, United States.
Jessica S WhittleDepartment of Emergency Medicine, University of Tennessee - Chattanooga, Chattanooga, TN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The typical approach to management of respiratory distress is focused on oxygen supplementation. However, additional oxygen alone does not improve outcomes, particularly in critically ill patients. Instead, supplemental oxygen can be associated with increased morbidities. We present the hypothesis that clinicians should focus on reducing the work of breathing early in the course of critical illness. Rather than simply supplementing oxygen, newer technologies including high flow nasal oxygen, may be utilized to increase the efficiency of gas exchange. By reducing the work of breathing, the cardiac workload can be reduced, thus relieving some excess physiologic stress and supporting the critically ill patient. To illustrate this point, we provided three clinical cases of respiratory failure from non-pulmonary origins; all cases displayed hemodynamic improvement due to reducing the work of breathing through high-velocity therapy prior to receiving definitive therapy for underlying pathologies.

Indexed as

acute respiratory failurecritical carehigh flow nasal cannulahigh flow oxygenhigh-velocity nasal insufflationhigh-velocity therapysepsis

Identifiers

PMID36530918
PMCPMC9755340

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.