Evidence map›Paper›PMID 36530900›Full record

ArticleFrontiers in medicine2022

Progressive fibrosing interstitial lung disease in rheumatoid arthritis: A retrospective study.

Anna Denis, Monique Henket, Marie Ernst, Nathalie Maes, Marie Thys, Céline Regnier, Olivier Malaise, Anne-Noëlle Frix, Fanny Gester, Colin Desir and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Anna DenisDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Monique HenketDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Marie ErnstDepartment of Biostatistics and Medico-Economic, CHU of Liège, Liège, Belgium.
Nathalie MaesDepartment of Biostatistics and Medico-Economic, CHU of Liège, Liège, Belgium.
Marie ThysDepartment of Biostatistics and Medico-Economic, CHU of Liège, Liège, Belgium.
Céline RegnierDepartment of Rheumatology, CHU of Liège, Liège, Belgium.
Olivier MalaiseDepartment of Rheumatology, CHU of Liège, Liège, Belgium.
Anne-Noëlle FrixDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Fanny GesterDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Colin DesirDepartment of Radiology, CHU of Liège, Liège, Belgium.
Paul MeunierDepartment of Radiology, CHU of Liège, Liège, Belgium.
Renaud LouisDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Michel MalaiseDepartment of Rheumatology, CHU of Liège, Liège, Belgium.
Julien GuiotDepartment of Pneumology, CHU of Liège, Liège, Belgium.
Centre Hospitalier Universitaire de Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Rheumatoid arthritis associated-interstitial lung disease (RA-ILD) is the most common pulmonary manifestation of rheumatoid arthritis (RA) and an important cause of mortality. In patients suffering from interstitial lung diseases (ILD) from different etiologies (including RA-ILD), a significant proportion is exhibiting a fibrotic progression despite immunosuppressive therapies, defined as progressive fibrosing interstitial lung disease (PF-ILD). Here, we report the frequency of RA-ILD and PF-ILD in all RA patients' cohort at University Hospital of Liège and compare their characteristics and outcomes. Methods: Patients were retrospectively recruited from 2010 to 2020. PF-ILD was defined based on functional, clinical and/or iconographic progression criteria within 24 months despite specific anti-RA treatment. Results: Out of 1,500 RA patients, about one third had high-resolution computed tomography (HRCT) performed, 89 showed RA-ILD and 48 PF-ILD. RA-ILD patients were significantly older than other RA patients (71 old of median age vs. 65, Conclusion: We identified a prevalence of PF-ILD of 3% in a general RA population. The PF-ILD cohort did not seem to be different in terms of demographic characteristics and mortality compared to RA-ILD patients who did not exhibit the progressive phenotype yet.

Indexed as

disease progressionepidemiological characteristicsinterstitial lung diseaselung fibrosisrheumatoid arthritissurvival

Identifiers

PMID36530900
PMCPMC9748274
OpenAlexW4311041166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.