Evidence map›Paper›PMID 36530369›Full record

ArticleSAGE open medical case reports2022

Rapid neurodevelopmental recovery after ART initiation in an infant with HIV encephalopathy.

Denise Quincardete, Muhammad Sidat, Gurpreet Seehra, Kiran Mitha, Uneisse Cassia, Alfeu Passanduca, Stella Langa, Sónia Martins, Beatriz Elias, W Chris Buck

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Denise QuincardeteHospital Central de Maputo, Maputo, Mozambique.
Muhammad SidatUniversidade Eduardo Mondlane, Maputo, Mozambique.ORCID https://orcid.org/0000-0001-8162-0102
Gurpreet SeehraDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Kiran MithaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Uneisse CassiaUniversidade Eduardo Mondlane, Maputo, Mozambique.
Alfeu PassanducaUniversidade Eduardo Mondlane, Maputo, Mozambique.
Stella LangaHospital Central de Maputo, Maputo, Mozambique.
Sónia MartinsUniversidade Eduardo Mondlane, Maputo, Mozambique.
Beatriz EliasHospital Central de Maputo, Maputo, Mozambique.
W Chris BuckUniversidade Eduardo Mondlane, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-6304-2262
Eduardo Mondlane University · MZMaputo Central Hospital · MZUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While there is ample evidence that antiretroviral therapy (ART) can improve cognitive outcomes in older children living with HIV, encephalopathy in infants has historically been considered an advanced disease presentation with less likelihood of neurodevelopmental recovery on treatment. More recent studies suggest that timely ART can halt encephalopathic disease progression and even lead to symptom resolution. Here we present a case of an HIV-positive infant diagnosed with encephalopathy who experienced impressive and rapid improvement with a multi-disciplinary care approach that included physical and occupational therapy and ART.

Indexed as

ARTencephalopathyHIVinfant

Identifiers

PMID36530369
PMCPMC9751151
OpenAlexW4312066013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.