Evidence map›Paper›PMID 36530262›Full record

ArticleACS omega2022

Investigation of the Effect of Turn Residues on Tetrapeptide Aldol Catalysts with β-Turn Propensity.

Albert Y Liu, Xavier A Calicdan, Gene N Glover, Xue Luo, Gage T Barroso, Brooke K Hoppe, Kelsey M Boyle, Leah S Witus

Abstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Albert Y LiuDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.ORCID https://orcid.org/0000-0002-3672-2035
Xavier A CalicdanDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.
Gene N GloverDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.
Xue LuoDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.ORCID https://orcid.org/0000-0001-5227-0481
Gage T BarrosoDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.
Brooke K HoppeDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.ORCID https://orcid.org/0000-0001-5562-1312
Kelsey M BoyleDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.
Leah S WitusDepartment of Chemistry, Macalester College, Saint Paul, Minnesota 55105, United States.ORCID https://orcid.org/0000-0002-2908-934X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide catalysts for a wide diversity of reaction types contain a common motif-residues that bias the sequence toward β-turn secondary structure. In this work, we explore what role that secondary structure plays in the catalysis of aldol reactions for primary amine tetrapeptide aldol catalysts. Using a lead tetrapeptide β-turn catalytic sequence, we varied the

Identifiers

PMID36530262
PMCPMC9753199

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.