Evidence map›Paper›PMID 36530085›Full record

ArticleJournal of Alzheimer's disease : JAD2023

Consumer and Healthcare Professional Led Priority Setting for Quality Use of Medicines in People with Dementia: Gathering Unanswered Research Questions.

Emily Reeve, Lynn Chenoweth, Mouna Sawan, Tuan Anh Nguyen, Lisa Kalisch Ellett, Julia Gilmartin-Thomas, Edwin Tan, Janet K Sluggett, Lyntara S Quirke, Kham Tran and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Emily ReeveQuality Use of Medicines and Pharmacy Research Centre, UniSA: Clinical and Health Sciences, University of South Australia, SA, Australia.
Lynn ChenowethCentre for Healthy Brain Ageing, University of New South Wales, Kensington, NSW, Australia.
Mouna SawanCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia.
Tuan Anh NguyenQuality Use of Medicines and Pharmacy Research Centre, UniSA: Clinical and Health Sciences, University of South Australia, SA, Australia.
Lisa Kalisch EllettQuality Use of Medicines and Pharmacy Research Centre, UniSA: Clinical and Health Sciences, University of South Australia, SA, Australia.
Julia Gilmartin-ThomasInstitute for Health and Sport, Victoria University, Melbourne, VIC, Australia.
Edwin TanSchool of Pharmacy, University of Sydney, Sydney, NSW, Australia.
Janet K SluggettCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia.
Lyntara S QuirkeConsumer advocate, Dementia Australia, Sydney, NSW, Australia.
Kham TranQuality Use of Medicines and Pharmacy Research Centre, UniSA: Clinical and Health Sciences, University of South Australia, SA, Australia.
Nagham AilabouniQuality Use of Medicines and Pharmacy Research Centre, UniSA: Clinical and Health Sciences, University of South Australia, SA, Australia.
Katherine CowanJames Lind Alliance, University of Southampton, Southampton, UK.
Ron SinclairConsumer advocate, Dementia Australia, Sydney, NSW, Australia.
Lenore de la PerrelleCollege of Education, Psychology and Social Work, Flinders University, SA, Australia.
Judy DeimelCentral Adelaide Local Health Network (CALHN) Memory Service, Adelaide, SA, Australia.
Josephine ToDivision of Aged Care, Rehabilitation and Palliative Care, Northern Adelaide Local Health Network, Adelaide, SA, Australia.
Stephanie DalyFamily Health Medical Group, Adelaide, SA, Australia.
Craig WhiteheadDivision of Rehabilitation, Aged and Palliative Care, Southern Adelaide Local Health Network, SA Health, Adelaide, SA, Australia.
Sarah N HilmerKolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine and Health, University of Sydney and Royal North Shore Hospital, St Leonards, NSW, Australia.

Funding

Advancing Alzheimer’s family caregiving interventions and research capacity in VietnamR01AG064688 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HINTON, WALTER LADSON, NGUYEN, HUONG · 2019 to 2023
$3.4M
NIA NIH HHS R01 AG064688
6 · The paper itself

Abstract

backgroundHistorically, research questions have been posed by the pharmaceutical industry or researchers, with little involvement of consumers and healthcare professionals.

objectiveTo determine what questions about medicine use are important to people living with dementia and their care team and whether they have been previously answered by research.

methodsThe James Lind Alliance Priority Setting Partnership process was followed. A national Australian qualitative survey on medicine use in people living with dementia was conducted with consumers (people living with dementia and their carers including family, and friends) and healthcare professionals. Survey findings were supplemented with key informant interviews and relevant published documents (identified by the research team). Conventional content analysis was used to generate summary questions. Finally, evidence checking was conducted to determine if the summary questions were 'unanswered'.

resultsA total of 545 questions were submitted by 228 survey participants (151 consumers and 77 healthcare professionals). Eight interviews were conducted with key informants and four relevant published documents were identified and reviewed. Overall, analysis resulted in 68 research questions, grouped into 13 themes. Themes with the greatest number of questions were related to co-morbidities, adverse drug reactions, treatment of dementia, and polypharmacy. Evidence checking resulted in 67 unanswered questions.

conclusionA wide variety of unanswered research questions were identified. Addressing unanswered research questions identified by consumers and healthcare professionals through this process will ensure that areas of priority are targeted in future research to achieve optimal health outcomes through quality use of medicines.

Indexed as

Biomedical ResearchDementiaAustraliaCaregiversHealth PersonnelHealth PrioritiesHumansCaregiversclinical decision-makingdementiadeprescriptionhealth services researchmultiple chronic conditionspharmacy researchpolypharmacy

Identifiers

PMID36530085
PMCPMC9912715

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.