ArticleArthritis care & research2023
Musculoskeletal Ultrasound and the Assessment of Disease Activity in Juvenile Idiopathic Arthritis.
Article in Arthritis care & research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Vision transformer-based ordinal model for semi-quantitative synovitis grading on musculoskeletal ultrasound: a retrospective study with internal and external validation.Annals of medicine · 2026Article
- From Hands to Imaging: The Emerging Role of Musculoskeletal Ultrasonography in Juvenile Idiopathic Arthritis Disease Activity Assessment.International journal of rheumatic diseases · 2026Article
- Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis.Arthritis care & research · 2026Article
- Musculoskeletal and nail ultrasound findings in children with psoriasis: a case-control study.Pediatric rheumatology online journal · 2026Article
- Application of a novel Musculoskeletal Ultrasound Sum Score (MUSS) in the follow-up of patients with juvenile idiopathic arthritis.Rheumatology (Oxford, England) · 2026Article
- Development and validation of subtype-specific simplified ultrasound assessment systems for juvenile idiopathic arthritis: a prospective observational study.Frontiers in pediatrics · 2026Article
- Sonographic and Disease Activity Findings Related With Medication Change in JIA: A Historical Cohort Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025Article
- Article
- Diagnostic Accuracy Study of the Pediatric-Specific Ultrasound Scoring System for the Knee Joint in Children With Juvenile Idiopathic Arthritis.Arthritis care & research · 2024Article
- The importance of ultrasound examination in care of juvenile idiopathic arthritis patients: 9 months follow-up study.Frontiers in pediatrics · 2024Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo determine the frequency of subclinical synovitis on musculoskeletal ultrasonography (MSUS) in juvenile idiopathic arthritis (JIA) and correlate patient- and provider-reported outcome measures with MSUS synovitis.
methodJIA patients with an active joint count (AJC) of >4 underwent a 42-joint MSUS performed at baseline and 3 months. B-mode and power Doppler images were obtained and scored (range 0-3) for each of the 42 joints. Outcomes evaluated included physician global assessment of disease activity (PhGA), patient global assessment of disease activity (PtGA), patient pain, Childhood Health Assessment Questionnaire (C-HAQ), and AJC. Subclinical synovitis was defined as synovitis detected by MSUS only. Generalized estimation equations were used to test the relationship between clinical arthritis (positive/negative) and subclinical synovitis (positive/negative). Spearman's correlation coefficients (r
resultsIn 30 patients, subclinical synovitis was detected in 30% of joints. Clinical arthritis of the fingers, wrists, and knee joints was significantly associated with MSUS synovitis in these joints. PtGA and the C-HAQ had a moderate (r
conclusionSubclinical synovitis was commonly observed in this cohort of JIA patients. The fair-to-moderate correlation of MSUS synovitis with patient- and provider-reported outcomes suggests that MSUS assesses a different, possibly more objective, domain not determined by traditional JIA outcome measurements.
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