Evidence map›Paper›PMID 36529851›Full record

ArticleSurgical endoscopy2023

Multi-society consensus conference and guideline on the treatment of gastroesophageal reflux disease (GERD).

Bethany J Slater, Amelia Collings, Rebecca Dirks, Jon C Gould, Alia P Qureshi, Ryan Juza, María Rita Rodríguez-Luna, Claire Wunker, Geoffrey P Kohn, Shanu Kothari and 20 more

Registry-linked trialAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06200961 (Use of Sedation-Free Transnasal Endoscopy to Improve Access and Lower Costs of Endoscopic Evaluations in a Bariatric Medical and Surgical Program), which is not on this map. Cited by 55 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 5 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06200961 narecruitingnot on this mapstarted 2026, after this paper: background citation

Use of Sedation-Free Transnasal Endoscopy to Improve Access and Lower Costs of Endoscopic Evaluations in a Bariatric Medical and Surgical Program

TypeinterventionalSponsorChristopher C. Thompson, MD, MScRan2026 to 2028Enrolled100ConditionsObesity, Obesity, Morbid, Obese, GI DisordersArmsTransnasal Endoscopy, Esophagogastroduodenoscopy
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. International Society for Diseases of the Esophagus consensus on management of the failed fundoplication.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Efficacy and Safety of Closure-Focused Anti-Reflux Mucoplasty Compared With Conventional ARMS: A Propensity Score-Matched Study (With Video).Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 5 countries.

Bethany J SlaterUniversity of Chicago Medicine, 5841 S. Maryland Avenue, MC 4062, Chicago, IL, USA. bjslater1@gmail.com.
Amelia CollingsDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Rebecca DirksDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Jon C GouldDivision of Minimally Invasive and Gastrointestinal Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Alia P QureshiDivision of General & GI Surgery, Foregut Surgery, Oregon Health & Science University, Portland, OR, USA.
Ryan JuzaDepartment of Surgery, University of Wisconsin, Madison, WI, USA.
María Rita Rodríguez-LunaResearch Institute Against Digestive Cancer (IRCAD) and ICube Laboratory, Photonics Instrumentation for Health, Strasbourg, France.
Claire WunkerSaint Louis University, St Louis, MO, USA.
Geoffrey P KohnDepartment of Surgery, Monash University, Melbourne, VIC, Australia.
Shanu KothariDepartment of Surgery, Prisma Health, Greenville, SC, USA.
Elizabeth CarslonVirginia Mason Medical Center, Seattle, WA, USA.
Stephanie WorrellUniversity of Arizona Health Sciences, Tucson, AZ, USA.
Ahmed M Abou-SettaDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Canada.
Mohammed T AnsariSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
Dimitrios I AthanasiadisDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Shaun DalyDepartment of Surgery, University of California, Irvine, Orange, CA, USA.
Francesca DimouWashington University in St. Louis, St. Louis, MO, USA.
Ivy N HaskinsDepartment of Surgery, University of Nebraska Medical Center, Omaha, USA.
Julie HongDepartment of Surgery, New York Presbyterian/Queens, Queens, USA.
Kumar KrishnanMassachusetts General Hospital, Boston, MA, USA.
Anne LidorDepartment of Surgery, University of Wisconsin, Madison, WI, USA.
Virginia LitleSection of Thoracic Surgery, Department of Cardiovascular Surgery, Intermountain Healthcare, Salt Lake City, UT, USA.
Donald LowVirginia Mason Medical Center, Seattle, WA, USA.
Anthony PetrickDepartment of General Surgery, Geisinger School of Medicine, Geisinger Medical Center, Danville, PA, USA.
Ian S SorianoDepartment of Surgery, University of California San Francisco School of Medicine, San Francisco, CA, USA.
Nirav ThosaniMcGovern Medical School, Center for Interventional Gastroenterology at UTHealth, Houston, TX, USA.
Amy TybergRutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Vic VelanovichDivision of Gastrointestinal Surgery, Tampa General, Tampa, FL, USA.
Ramon VilallongaEndocrine, Metabolic and Bariatric Unit, General Surgery Department, Vall d'Hebron University Hospital, Center of Excellence for the EAC-BC, Universitat Autònoma de Barcelona, Barcelona, Spain.
Jeffrey M MarksCase Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Indiana University School of MedicineUniversity of Wisconsin–Madison · USVirginia Mason Medical Center · USGeisinger Medical Center · USIndiana University – Purdue University Indianapolis · USInstitut de Recherche contre les Cancers de l’Appareil Digestif · FRIntermountain Healthcare · USJohnson University · USMassachusetts General Hospital · USMedical College of Wisconsin · USMonash University · AUNew York Hospital Queens · USOregon Health & Science University · USPrisma Health · USSaint Louis University · USTampa General Hospital · USThe University of Texas Health Science Center at Houston · USUniversitat Autònoma de Barcelona · ESUniversity Hospitals of Cleveland · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastroesophageal reflux disease (GERD) is one of the most common diseases in North America and globally. The aim of this guideline is to provide evidence-based recommendations regarding the most utilized and available endoscopic and surgical treatments for GERD.

methodsSystematic literature reviews were conducted for 4 key questions regarding the surgical and endoscopic treatments for GERD in adults: preoperative evaluation, endoscopic vs surgical or medical treatment, complete vs partial fundoplication, and treatment for obesity (body mass index [BMI] ≥ 35 kg/m

resultsThe consensus provided 13 recommendations. Through the development of these evidence-based recommendations, an algorithm was proposed for aid in the treatment of GERD. Patients with typical symptoms should undergo upper endoscopy, manometry, and pH-testing; additional testing may be required for patients with atypical or extra-esophageal symptoms. Patients with normal or abnormal findings on manometry should consider undergoing partial fundoplication. Magnetic sphincter augmentation or fundoplication are appropriate surgical procedures for adults with GERD. For patients who wish to avoid surgery, the Stretta procedure and transoral incisionless fundoplication (TIF 2.0) were found to have better outcomes than proton pump inhibitors alone. Patients with concomitant obesity were recommended to undergo either gastric bypass or fundoplication, although patients with severe comorbid disease or BMI > 50 should undergo Roux-en-Y gastric bypass for the additional benefits that follow weight loss.

conclusionUsing the recommendations an algorithm was developed by this panel, so that physicians may better counsel their patients with GERD. There are certain patient factors that have been excluded from included studies/trials, and so these recommendations should not replace surgeon-patient decision making. Engaging in the identified research areas may improve future care for GERD patients.

Indexed as

Gastric BypassGastroesophageal RefluxAdultEndoscopy, GastrointestinalFundoplicationHumansObesityTreatment OutcomeAntireflux surgeryFundoplicationGastroesophageal refluxGERDObesityProton pump inhibitor

Identifiers

PMID36529851
OpenAlexW4311851746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.