Evidence map›Paper›PMID 36529830›Full record

ArticleJournal of assisted reproduction and genetics2023

Association between donor gamete use and supernumerary embryo disposition decisions.

Shelun Tsai, Jenna S Hynes, Nicole Zanolli, Douglas Raburn, Anne Z Steiner

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. One size does not fit all: the personal nature of completed embryo donation.Journal of assisted reproduction and genetics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shelun TsaiDivision of Reproductive Endocrinology and Infertility, Duke Health Center, 5601 Arringdon Park Dr., Suite 210, Morrisville, NC, 27560, USA. set9051@med.cornell.edu.ORCID http://orcid.org/0000-0003-1487-9039
Jenna S HynesDivision of Reproductive Endocrinology and Infertility, Duke Health Center, 5601 Arringdon Park Dr., Suite 210, Morrisville, NC, 27560, USA.
Nicole ZanolliDuke University School of Medicine, Duke University Medical Center, 8 Searle Center Drive, Durham, NC, 27710, USA.
Douglas RaburnDivision of Reproductive Endocrinology and Infertility, Duke Health Center, 5601 Arringdon Park Dr., Suite 210, Morrisville, NC, 27560, USA.
Anne Z SteinerDivision of Reproductive Endocrinology and Infertility, Duke Health Center, 5601 Arringdon Park Dr., Suite 210, Morrisville, NC, 27560, USA.
Cornell University · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to determine if donor gamete use is associated with patients' decisions regarding disposition of supernumerary embryos.

methodsPatients who intended to undergo an IVF cycle at a single academic center signed an embryo disposition consent form to indicate their disposition preferences for any supernumerary embryos. A retrospective chart review was performed to obtain the embryo disposition declarations and demographic information. The primary outcome was the distribution of embryo disposition choices between patients who used donor gametes compared to patients who did not use donor gametes. Fisher's exact test was used to compare groups. Logistic regression models were created to determine the association between donor gamete use and disposition decision after adjusting for patient age, body mass index, and nulliparity.

resultsFive hundred six patients were included. Ninety-one (18.0%) patients used donor gametes [46 (9.0%) donor oocytes, 52 (10.3%) donor sperm]. Patients using donor gametes differed from those not using donor gametes when making decisions concerning death of the patient (P < 0.01), simultaneous death (P = 0.04), separation (P < 0.01), discontinuation of ART (P = 0.01), and time-limited storage (P < 0.01). Most patients, regardless of donor or autologous gamete use, awarded embryos to themselves or their partner if given the option. For patients who did not choose this option, excess embryos were generally awarded to research or discarded rather than donating to another couple. Patients using donor gametes were more likely to award embryos to research over discarding.

conclusionPatients using donor gametes made different choices regarding supernumerary embryo disposition compared to patients not using donor gametes.

Indexed as

Embryo DispositionFertilization in VitroAnimalsGerm CellsMaleRetrospective StudiesSemenDonor gametesEmbryo dispositionSupernumerary embryos

Identifiers

PMID36529830
PMCPMC9935759
OpenAlexW4311931680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.