Evidence map›Paper›PMID 36529736›Full record

ArticleBMC geriatrics2022

Investigating the relationship between specific executive functions and functional decline among community-dwelling older adults: results from a prospective pilot study.

Emilie Verreckt, Elise Grimm, Stefan Agrigoroaei, Marie de Saint Hubert, Pierre Philippot, Gérald Cremer, Didier Schoevaerdts

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Lost in Thought or Just Lonely? Everyday Cognitive Competence in Middle Adulthood.European journal of investigation in health, psychology and education · 2025
    Article
  8. The impact of cognitive-motor interference on balance and gait in hearing-impaired older adults: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024
    Review
  9. Article
  10. Observational
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Emilie VerrecktGeriatric Department, CHU UCL Namur, Site Godinne, Av. Dr. G. Therasse, 1, 5530, Yvoir, Belgium. Emilie.verreckt@chuuclnamur.uclouvain.be.
Elise GrimmPsychological Sciences Research Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Stefan AgrigoroaeiPsychological Sciences Research Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Marie de Saint HubertGeriatric Department, CHU UCL Namur, Site Godinne, Av. Dr. G. Therasse, 1, 5530, Yvoir, Belgium.
Pierre PhilippotPsychological Sciences Research Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Gérald CremerGeriatric Department, CHU UCL Namur, Site Godinne, Av. Dr. G. Therasse, 1, 5530, Yvoir, Belgium.
Didier SchoevaerdtsGeriatric Department, CHU UCL Namur, Site Godinne, Av. Dr. G. Therasse, 1, 5530, Yvoir, Belgium.
CHU Dinant Godinne UCL Namur · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs cognitive functions and, more specifically, executive functions (EF) seem to influence autonomy among the elderly, we investigated the role of each of the five EF sub-components (inhibition, spontaneous flexibility, reactive flexibility, planning, and updating in working memory) for the risk of functional decline.

methodA total of 137 community-dwelling participants over 75 years of age were included in a prospective cohort study and assigned to three groups: individuals with neuro-degenerative cognitive disorders, those having cognitive disorders with non-degenerative aetiology, and a control group without any cognitive problems. We measured each EF sub-component and assessed functional decline by evaluating basic (b-ADL) and instrumental activities of daily living (i-ADL) at baseline and 6 months later. We conducted three separate multiple logistic regression models to examine the extent to which the five EF facets predicted overall functional decline at the end of the follow-up period.

resultsWe found that people who exhibited a decline in b-ADLs or/and i-ADLs over 6 months had worse performance on inhibition and two flexibility tasks than those who did not experience a decline. The results suggest that decliners have more difficulties in managing unforeseen events. Inhibition and updating in working memory predicted a decline in b-ADL while spontaneous and reactive flexibilities predicted a decline in i-ADL.

conclusionIn our sample, specific executive dysfunctions were associated with a decline in functional status. With respect to the risk of decline in b-ADL, deficits in inhibition may represent a risk factor, as it regulates over-learned activities. Bothtypes of flexibility, which allow the shifting and generating of adaptive responses, predicted decline in i-ADL. In sum, paying more attention to particular EF profiles would help clinicians to anticipate some aspects of functional decline.

Indexed as

Activities of Daily LivingIndependent LivingAgedExecutive FunctionHumansPilot ProjectsProspective StudiesActivities of daily living (ADL)AgingAutonomyCognitive assessmentFlexibilityInhibitionPlanningUpdating in working memory

Identifiers

PMID36529736
PMCPMC9762049
OpenAlexW4312066113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.