Evidence map›Paper›PMID 36529695›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Hyaluronic Acid-Guided Cerasome Nano-Agents for Simultaneous Imaging and Treatment of Advanced Atherosclerosis.

Qian Ma, Sijing Wu, Ling Yang, Yaohua Wei, Chaoyong He, Wenshan Wang, Yingxin Zhao, Zhijian Wang, Shiwei Yang, Dongmei Shi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  5. Review
  6. Review
  7. TargetedImmunotherapy advances · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Advances in Atherosclerosis Theranostics Harnessing Iron Oxide-Based Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Qian MaDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Sijing WuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Ling YangBeijing Inno Medicine Co. Ltd., Beijing, 100195, P. R. China.
Yaohua WeiBeijing Inno Medicine Co. Ltd., Beijing, 100195, P. R. China.
Chaoyong HeBeijing Inno Medicine Co. Ltd., Beijing, 100195, P. R. China.
Wenshan WangBeijing Inno Medicine Co. Ltd., Beijing, 100195, P. R. China.
Yingxin ZhaoDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Zhijian WangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Shiwei YangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Dongmei ShiDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Yuyang LiuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Zhiming ZhouDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Jiefang SunBeijing Inno Medicine Co. Ltd., Beijing, 100195, P. R. China.ORCID 0000-0002-5279-7467
Yujie ZhouDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 100029, Beijing, P. R. China.
Capital Medical University · CNBeijing VDJBio (China) · CN

Funding

Beijing Municipal Medical Research Institute Public Welfare Development Pilot ProjectBeijing Municipal Natural Science Foundation 7182048National Natural Science Foundation of China 81400324
6 · The paper itself

Abstract

Early noninvasive screening and regression therapy for vulnerable atherosclerotic plaques remain challenging. In this study, it is aimed to develop a new approach for the active targeting of atherosclerotic plaques with nano-agents to aid imaging and treatment. Biocompatible hyaluronic acid (HA)-guided cerasomes are generated to selectively target CD44-positive cells within the plaque in in vitro studies and in vivo testing in Apoe

Indexed as

AtherosclerosisNanoparticle Drug Delivery SystemPlaque, AtheroscleroticAnimalsHyaluronic AcidMagnetic Resonance ImagingMiceHyaluronic AcidNanoparticle Drug Delivery Systemactive targeting deliveryatherosclerosiscerasomesdiagnosis and treatmenthyaluronic acid

Identifiers

PMID36529695
PMCPMC9929131
OpenAlexW4311869892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.