Evidence map›Paper›PMID 36529618›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2023

Shifts in Gender-Related Medical Requests by Transgender and Gender-Diverse Adolescents.

Ariel Cohen, Veronica Gomez-Lobo, Laura Willing, David Call, Lauren F Damle, Lawrence J D'Angelo, Amber Song, John F Strang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Research methods at the intersection of gender diversity and autism: A scoping review.Autism : the international journal of research and practice · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Gender detransition: A critical review of the literature.Actas espanolas de psiquiatria · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ariel CohenPediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland; Department of Surgery, Children's National Hospital, Washington, DC; Department of Pediatric and Adolescent Gynecology, Kaiser Permanente Mid-Atlantic Permanente Medical Group, Washington, DC. Electronic address: acohen3@childrensnational.org.
Veronica Gomez-LoboPediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland; Department of Surgery, Children's National Hospital, Washington, DC.
Laura WillingGender Development Program, Children's National Hospital, Washington, DC; Department of Pediatrics, George Washington University School of Medicine, Washington, DC; Departments of Psychiatry, and Behavioral Sciences, George Washington University School of Medicine, Washington, DC.
David CallGender Development Program, Children's National Hospital, Washington, DC; Department of Pediatrics, George Washington University School of Medicine, Washington, DC; Departments of Psychiatry, and Behavioral Sciences, George Washington University School of Medicine, Washington, DC.
Lauren F DamleDepartment of Surgery, Children's National Hospital, Washington, DC; Department of Women and Infant Services, MedStar Washington Hospital Center, Washington, DC.
Lawrence J D'AngeloDepartment of Pediatrics, George Washington University School of Medicine, Washington, DC; Divisions of Adolescent and Young Adult Medicine, George Washington University School of Medicine, Washington, DC.
Amber SongGender Development Program, Children's National Hospital, Washington, DC; Division of Neuropsychology, Center for Autism Spectrum Disorders, Children's National Hospital, Washington, DC; Center for Neuroscience, Children's National Research Institute, Children's National Hospital, Washington, DC.
John F StrangGender Development Program, Children's National Hospital, Washington, DC; Department of Pediatrics, George Washington University School of Medicine, Washington, DC; Departments of Psychiatry, and Behavioral Sciences, George Washington University School of Medicine, Washington, DC; Division of Neuropsychology, Center for Autism Spectrum Disorders, Children's National Hospital, Washington, DC; Center for Neuroscience, Children's National Research Institute, Children's National Hospital, Washington, DC.

Funding

Pediatric and Adolescent Gynecology Training ProgramZIEHD008985 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GOMEZ-LOBO, VERONICA · 2022 to 2025
$9.3M
Pediatric and Adolescent Gynecology Training ProgramZIAHD008985 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GOMEZ-LOBO, VERONICA · 2019 to 2021
$5.3M
Intramural NIH HHS ZIA HD008985
6 · The paper itself

Abstract

purposeGender-affirming hormones and/or surgeries seeking to change the body can have potentially lasting effects. Changes in requests for these therapies among gender-diverse youth are not well-understood. The study aim is to characterize factors associated with shifts in gender-related medical requests.

methodsThis mixed-methods study used retrospective chart review and qualitative interviews with clinicians. Of 130 youth receiving clinical gender care at Children's National Hospital, 68 met inclusion criteria. Qualitative interview analysis was performed to identify patterns and themes around shifts in gender-related medical requests over time. Statistical analysis employed chi-square and t-tests to compare characteristics in the shift versus no-shift groups and kappa statistics to calculate qualitative coding agreement.

resultsOf the 68 youth followed over time (mean age 15.11 years, 47% autistic, 22% nonbinary), 20 (29%) reported a shift in request. No significant differences were found by age, autism status, or designated sex at birth. More youth with shifts were nonbinary (p = .012). Six shift profiles were identified from qualitative interviews with excellent reliability (κ = 0.865). Four of the profiles reflect shifts in request prior to starting treatment (85% sample); two involved shifts after commencing treatment (15%). The most common profile reflected a medical request that was made, withdrawn, and re-requested (45%). DISCUSSION: Shifts in gender-affirming medical requests by gender-diverse youth may not be uncommon during the adolescent's gender discernment process, and may more likely occur among nonbinary youth. Many individuals who experience shifts away from medical treatment may later resume the request.

Indexed as

Transgender PersonsTranssexualismAdolescentFemaleGender IdentityHumansMaleReproducibility of ResultsRetrospective StudiesAdolescenceGender-affirming hormonesGender-affirming surgeryGender diverseGender dysphoriaGender incongruenceTransgender

Identifiers

PMID36529618
PMCPMC9974924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.