Evidence map›Paper›PMID 36528621›Full record

ArticleJournal of medical case reports2022

Breast neuroendocrine tumor arising in the axilla of a man: a case report.

Kosei Kimura, Shigeru Kawabata, Hiroyo Oku, Ayana Ikari, Tomo Tominaga, Saki Takai, Junna Sakane, Michiaki Tanaka, Chinatsu Aoki, Monika Ota and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Incidental finding of solitary fibrous tumor of male breast: case report and review of literature.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
  4. Axillary Neuroendocrine Carcinoma: A Case Report and Review of the Literature.Journal of investigative medicine high impact case reports
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Kosei KimuraDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan. kosei.kimura@ompu.ac.jp.
Shigeru KawabataDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Hiroyo OkuDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Ayana IkariDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Tomo TominagaDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Saki TakaiDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Junna SakaneDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Michiaki TanakaDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Chinatsu AokiDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Monika OtaDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Erika MinamiDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Yoshinobu HiroseDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Sang-Woong LeeDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Mitsuhiko IwamotoDepartment of Breast and Endocrine Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Osaka University of Pharmaceutical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccessory breast carcinomas of the axilla of males are rare, and primary breast neuroendocrine tumors (BNETs) are rare as well. We present a case of a BNET arising in the axilla of a man. CASE PRESENTATION: A 64-year-old Japanese man presented with a hard 15-mm mass in the axilla and axillary lymph node swelling. Histopathological examination of the incisional biopsy specimen revealed a neuroendocrine carcinoma. Therefore, wide radical excision of the axillary tumor and axillary lymph node dissection were performed. Hematoxylin and eosin staining showed that the solid tumor was mainly located in the subcutaneous adipose tissues and appeared to invade the skin. The tumor phenotypes were positive for CAM 5.2, synaptophysin, estrogen receptor, progesterone receptor, and GATA-binding protein 3; they were negative for human epidermal growth receptor 2. The neuroendocrine component comprised more than 90% of the tumor, and the Ki-67 index was 21%. These results indicated that the tumor was a BNET. This patient underwent adjuvant chemotherapy, endocrine therapy, and radiotherapy.

conclusionsBNET cases in males are rare. The clinical and histological criteria as well as treatment for these rare cases are discussed.

Indexed as

Breast NeoplasmsNeuroendocrine TumorsAxillaChemotherapy, AdjuvantHumansLymph Node ExcisionLymph NodesMaleMiddle AgedAccessory breast carcinomaAxillary tumorMale breast cancerNeuroendocrine tumor

Identifiers

PMID36528621
PMCPMC9759905
OpenAlexW4312066004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.