Evidence map›Paper›PMID 36528024›Full record

ArticleCurrent biology : CB2023

Genetic architecture and evolution of color variation in American black bears.

Emily E Puckett, Isis S Davis, Dawn C Harper, Kazumasa Wakamatsu, Gopal Battu, Jerrold L Belant, Dean E Beyer, Colin Carpenter, Anthony P Crupi, Maria Davidson and 32 more

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  10. Taking a color photo: A homozygous 25-bp deletion inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Metalation and activation of ZnBiophysics reviews · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 3 countries.

Emily E PuckettDepartment of Biological Sciences, University of Memphis, Memphis, TN 38152, USA. Electronic address: emily.puckett@memphis.edu.
Isis S DavisDepartment of Biological Sciences, University of Memphis, Memphis, TN 38152, USA.
Dawn C HarperDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Kazumasa WakamatsuInstitute for Melanin Chemistry, Fujita Health University, Toyoake, Japan.
Gopal BattuHudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA.
Jerrold L BelantDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA.
Dean E BeyerDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA.
Colin CarpenterWest Virginia Division of Natural Resources, Beckley, WV 25801, USA.
Anthony P CrupiDivision of Wildlife Conservation, Alaska Department of Fish and Game, Douglas, Juneau, AK 99824, USA.
Maria DavidsonThe Louisiana Department of Wildlife and Fisheries, Baton Rouge, LA 70898, USA.
Christopher S DePernoDepartment of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695-7646, USA.
Nicholas FormanNew Mexico Department of Game and Fish, Santa Fe, NM 87507, USA.
Nicholas L FowlerDivision of Wildlife Conservation, Alaska Department of Fish and Game, Douglas, Juneau, AK 99824, USA.
David L GarshelisMinnesota Department of Natural Resources, Grand Rapids, MN 55744, USA; IUCN SSC Bear Specialist Group.
Nicholas GouldDepartment of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695-7646, USA.
Kerry GuntherNational Park Service, Yellowstone National Park, WY 82190-0168, USA.
Mark HaroldsonU.S. Geological Survey, Northern Rocky Mountain Science Center, Interagency Grizzly Bear Study Team, Bozeman, MT 59715, USA.
Shosuke ItoInstitute for Melanin Chemistry, Fujita Health University, Toyoake, Japan.
David KockaVirginia Department of Wildlife Resources, Verona, VA 24482, USA.
Carl LackeyNevada Department of Wildlife, Reno, NV 89512, USA.
Ryan LeahyNational Park Service, Yosemite National Park Wildlife Management, Yosemite, CA 95389, USA.
Caitlin Lee-RoneyNational Park Service, Yosemite National Park Wildlife Management, Yosemite, CA 95389, USA.
Tania LewisNational Park Service, Glacier Bay National Park, Gustavus, AK 99826, USA.
Ashley LuttoU.S. Fish and Wildlife Service, Kenai National Wildlife Refuge, Soldotna, AK 99669, USA.
Kelly McGowanDepartment of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Colleen OlfenbuttelNorth Carolina Wildlife Resources Commission, Raleigh, NC 27699, USA.
Mike OrlandoFlorida Fish and Wildlife Conservation Commission, Tallahassee, FL 32399, USA.
Alexander PlattDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Matthew D PollardDepartment of Biological Sciences, University of Memphis, Memphis, TN 38152, USA.
Megan RamakerHudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA.
Heather ReichNevada Department of Wildlife, Reno, NV 89512, USA.
Jaime L SajeckiVirginia Department of Wildlife Resources, Verona, VA 24482, USA.
Stephanie K SellDivision of Wildlife Conservation, Alaska Department of Fish and Game, Douglas, Juneau, AK 99824, USA.
Jennifer StrulesDepartment of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695-7646, USA.
Seth ThompsonVirginia Department of Wildlife Resources, Verona, VA 24482, USA.
Frank van ManenU.S. Geological Survey, Northern Rocky Mountain Science Center, Interagency Grizzly Bear Study Team, Bozeman, MT 59715, USA.
Craig WhitmanU.S. Geological Survey, Northern Rocky Mountain Science Center, Interagency Grizzly Bear Study Team, Bozeman, MT 59715, USA.
Ryan WilliamsonNational Park Service, Great Smoky Mountains National Park, Gatlinburg, TN 37738, USA.
Frederic WinslowNew Mexico Department of Game and Fish, Santa Fe, NM 87507, USA.
Christopher B KaelinDepartment of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Michael S MarksDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Departments of Pathology and Laboratory Medicine and of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gregory S BarshHudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA; Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA.
National Park Service · USAlaska Department of Fish and Game · USHudsonAlpha Institute for Biotechnology · USNorth Carolina State University · USUnited States Geological Survey · USUniversity of Memphis · USVirginia Department of Game and Inland Fisheries · USChildren's Hospital of Philadelphia · USFujita Health University · JPMichigan State University · USNevada Department of Wildlife · USNew Mexico Department of Game and FishStanford University · USFlorida Fish and Wildlife Conservation Commission · USInternational Union for Conservation of Nature (Bangladesh) · BDLouisiana Department of Wildlife and Fisheries · USNorth Carolina Wildlife Resources Commission · USUnited States Fish and Wildlife Service · USUniversity of Pennsylvania · USWest Virginia Division of Natural Resources · US

Funding

Genetic and molecular basis for variation in human skin pigmentationR01AR076241 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI MARKS, MICHAEL S, OANCEA, ELENA · 2020 to 2024
$5.5M
Integrative Genomic Analyses of Human Evolution and Adaptation in AfricaR35GM134957 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2020 to 2024
$2.7M
Melanocortin signaling: genetic insight from X-linked color mutations in non-model organismsR01AR067925 · NIAMS · HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY · PI BARSH, GREGORY STEFAN · 2015 to 2019
$1.6M
NIAMS NIH HHS R01 AR067925NIAMS NIH HHS R01 AR076241NIGMS NIH HHS R35 GM134957
6 · The paper itself

Abstract

Color variation is a frequent evolutionary substrate for camouflage in small mammals, but the underlying genetics and evolutionary forces that drive color variation in natural populations of large mammals are mostly unexplained. The American black bear, Ursus americanus (U. americanus), exhibits a range of colors including the cinnamon morph, which has a similar color to the brown bear, U. arctos, and is found at high frequency in the American southwest. Reflectance and chemical melanin measurements showed little distinction between U. arctos and cinnamon U. americanus individuals. We used a genome-wide association for hair color as a quantitative trait in 151 U. americanus individuals and identified a single major locus (p < 10

Indexed as

UrsidaeAnimalsGene FlowGenetic VariationGenomeGenome-Wide Association Studyfunctional phylogeographyGWASmelan-bmigrationOCA3TYRP1

Identifiers

PMID36528024
PMCPMC10039708
OpenAlexW4311860128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.