Changes in Oxygenation Levels During Moderate Altitude Simulation (Hypoxia-Induced): A Pilot Study Investigating the Impact of Skin Pigmentation in Pulse Oximetry.

Victor Ochoa-Gutierrez, Selene Guerrero-Zuñiga, Julien Reboud, Mauro Pazmino-Betancourth, Andrew R Harvey, Jonathan M Cooper

Open access · greenAbstract read

PubMed Publisher

In one paragraph

Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.6field-weighted citation impact, top 29% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Victor Ochoa-GutierrezDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow, UK. v.ochoa-gutierrez.1@research.gla.ac.uk.

Selene Guerrero-ZuñigaNational Institute of Respiratory Diseases (INER), Mexico City, Mexico.

Julien ReboudDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow, UK.

Mauro Pazmino-BetancourthBiodiversity, Animal Health & Comparative Medicine, MVLS, University of Glasgow, Glasgow, UK.

Andrew R HarveySchool of Physics and Astronomy, University of Glasgow, Glasgow, UK.

Jonathan M CooperDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow, UK.

University of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current COVID-19 pandemic has shown us that the pulse oximeter is a key medical device for monitoring blood-oxygen levels non-invasively in patients with chronic or acute illness. It has also emphasised limitations in accuracy for individuals with darker skin pigmentation, calling for new methods to provide better measurements. The aim of our study is to identify the impact of skin pigmentation on pulse oximeter measurements. We also explored the benefits of a multi-wavelength approach with an induced change of arterial oxygen saturation. A total of 20 healthy volunteers were recruited. We used time domain diffuse reflectance spectroscopy (TDDRS) from a broad band light source, collecting spectra from the index finger along with three different pulse oximeters used simultaneously for monitoring purposes. Five acute hypoxic events were induced by administering 11% FiO

Indexed as

COVID-19Skin PigmentationAltitudeHumansHypoxiaOximetryOxygenPandemicsPilot ProjectsOxygenArterial oxygen saturationMultiple wavelength spectrophotometerSkin typesTime domain diffuse reflectance spectroscopy

Identifiers

PMID36527668

DOI10.1016/j.cmpb.2019.105237

OpenAlexW4312019569

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.