Evidence map›Paper›PMID 36527649›Full record

ArticleAdvances in experimental medicine and biology2022

Evaluation of Betulinic Acid Derivatives as PET Tracers for Hypoxia-Induced Carbonic Anhydrase IX (CA IX) Expression.

V Haupt, D Gündel, E Prell, M Kahnt, S Sommerwerk, A Riemann, R Paschke, R Csuk, A Odparlik, O Thews

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Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

V HauptJulius-Bernstein-Institute of Physiology, University of Halle, Halle (Saale), Germany.
D GündelDepartment of Nuclear Medicine, University Hospital Halle, Halle (Saale), Germany.
E PrellDepartment of Nuclear Medicine, University Hospital Halle, Halle (Saale), Germany.
M KahntDepartment of Organic Chemistry, University of Halle, Halle (Saale), Germany.
S SommerwerkDepartment of Organic Chemistry, University of Halle, Halle (Saale), Germany.
A RiemannJulius-Bernstein-Institute of Physiology, University of Halle, Halle (Saale), Germany.
R PaschkeBiozentrum, University of Halle, Halle (Saale), Germany.
R CsukDepartment of Organic Chemistry, University of Halle, Halle (Saale), Germany.
A OdparlikDepartment of Nuclear Medicine, University Hospital Halle, Halle (Saale), Germany.
O ThewsJulius-Bernstein-Institute of Physiology, University of Halle, Halle (Saale), Germany. oliver.thews@medizin.uni-halle.de.
University Hospital in Halle · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive visualisation of the expression of hypoxia-related proteins, such as carbonic anhydrase IX (CA IX), by positron emission tomography (PET) could provide important information on the oxygenation status of tumours. Since betulinic acid derivatives bind specifically to CA IX the aim of the study was the development betulinic acid-based

Indexed as

Betulinic AcidPositron Emission Tomography Computed TomographyAnimalsAntigens, NeoplasmCarbonic Anhydrase IXHypoxiaMalePositron-Emission TomographyRatsSulfonic AcidsAntigens, NeoplasmBetulinic AcidCarbonic Anhydrase IXsulfamic acidSulfonic AcidsAT-1 cellsB-DOTABS-DOTATumor oxygenation statusWalker-256 cells

Identifiers

PMID36527649
OpenAlexW4312019177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.