Evidence map›Paper›PMID 36527616›Full record

ArticleAdvances in experimental medicine and biology2022

Impaired Cognitive Performance in Mice Exposed to Prolonged Hyperoxia.

Geisa Ortet, Lei Ma, J Sebastian Garcia-Medina, Joseph LaManna, Kui Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Geisa OrtetDepartment of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH, USA.
Lei MaSchool of Electronic Information Science and Technology, Nantong University, Nantong, Jiangsu Province, China.
J Sebastian Garcia-MedinaDepartment of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH, USA.
Joseph LaMannaDepartment of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH, USA.
Kui XuDepartment of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH, USA. Kxx@case.edu.
Case Western Reserve University · USNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supplementation of oxygen at concentrations significantly above environmental level for prolonged periods may lead to hyperoxia and tissue toxicity. The mammalian brain undergoes structural and functional changes during adaptation to hypoxia and hyperoxia. In this study we investigated the effect of prolonged hyperoxic exposure on cognitive and motor performance in mice. Two-month-old male mice were placed in either hyperoxic (50% O

Indexed as

HyperoxiaAdaptation, PhysiologicalAnimalsCognitionHypoxiaMaleMammalsMiceOxygenOxygenCognitive functionOxidative damageOxygen supplementationSpontaneous alternating performance

Identifiers

PMID36527616
OpenAlexW4312019136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.