Evidence map›Paper›PMID 36527582›Full record

ArticleGeroScience2023

The effect of a digital health coaching and health education protocol on cognition in adults at-risk for Alzheimer's.

Anthony Campitelli, Joshua L Gills, Megan D Jones, Sally Paulson, Jennifer Myers, Kelsey Bryk, Erica N Madero, Jordan M Glenn, Charlie H Rodgers, Jenova A Kempkes and 1 more

Open access · hybridAbstract read
In one paragraph

Article in GeroScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Anthony CampitelliDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA.ORCID http://orcid.org/0000-0001-9191-9263
Joshua L GillsDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA.ORCID http://orcid.org/0000-0003-3321-4120
Megan D JonesDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA.ORCID http://orcid.org/0000-0003-1023-310X
Sally PaulsonSt. Elizabeth Healthcare, Edgewood, KY, USA.ORCID http://orcid.org/0000-0001-8411-5259
Jennifer MyersNeurotrack Technologies, Inc, Redwood City, CA, USA.
Kelsey BrykNeurotrack Technologies, Inc, Redwood City, CA, USA.ORCID http://orcid.org/0000-0003-3926-230X
Erica N MaderoNeurotrack Technologies, Inc, Redwood City, CA, USA.ORCID http://orcid.org/0000-0002-5112-2441
Jordan M GlennNeurotrack Technologies, Inc, Redwood City, CA, USA.ORCID http://orcid.org/0000-0002-2563-4291
Charlie H RodgersDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA.
Jenova A KempkesDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA.
Michelle GrayDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA. rgray@uark.edu.ORCID http://orcid.org/0000-0001-5721-9087
University of Arkansas at Fayetteville · USNeurotrack Technologies (United States) · USSt. Elizabeth Healthcare · US

Funding

Digital multidomain lifestyle intervention to address cognitive health and modifiable risk factors for Alzheimer's diseaseR44AG063672 · NIA · NEUROTRACK TECHNOLOGIES, INC. · PI GLENN, JORDAN · 2019 to 2022
$3.3M
NIA NIH HHS R44 AG063672
6 · The paper itself

Abstract

Several modifiable lifestyle factors have been linked to cognitive ability and the risk of developing Alzheimer's disease and related dementias (ADRD). Health coaching (HC) is an intervention that addresses lifestyle factors associated with cognition. The effectiveness of an HC protocol was evaluated and compared with a health education (HE) intervention, representing the current standard of care, in a sample of 216 adults between the ages of 45 and 75 years who were at-risk for developing ADRD. Outcomes examined were global cognition, neuropsychological cognition, and Alzheimer's risk. HC participants received personalized coaching from a health coach focusing on nutrition, physical activity, sleep, stress, social engagement, and cognitive activity. HE participants received biweekly education materials focusing on the same modifiable lifestyle factors addressed by HC. Participants were assessed at baseline and again 4 months later. Self-reported global cognition scores improved only in the HC group (16.18 to 15.52, p = .03) and neuropsychological cognitive ability improved in the HE group (104.48 to 108.76, p < .001). When non-adherence in the HC group was accounted for, however, the mean change in neuropsychological score was similar between groups (p > .05), self-reported global cognition demonstrated an even larger mean improvement in the HC group (16.20 to 15.41, p = .01), and the HC group saw an improvement in ADRD protective risk score (- 10.39 to - 11.45, p = .007). These results indicate that HC and HE can both improve cognition, but HC may be more effective and may yield increased protection against ADRD risk.

Indexed as

Alzheimer DiseaseMentoringAgedCognitionHealth EducationHumansLife StyleAlzheimer’s diseaseAlzheimer’s riskCognitionHealth coaching

Identifiers

PMID36527582
PMCPMC9886777
OpenAlexW4311820982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.