Evidence map›Paper›PMID 36527576›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2023

High performance of the automated ADVIA Centaur Systems SARS-CoV-2 Antigen Assay in nasopharyngeal samples with high viral load.

Esther Ríos, Sara Medrano, Mar Alvarez, María José Valderrama, Luis Vallejo, Alberto Delgado-Iribarren, Esther Culebras

Open access · hybridAbstract read
In one paragraph

Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Esther RíosDepartment of Medicine, Facultad de Medicina, Universidad Complutense Madrid, Plaza Ramón y Cajal S/N, Madrid, 28040, Spain. erios02@ucm.es.
Sara MedranoDepartment of Clinical Microbiology, Instituto de Investigación Sanitaria Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Mar AlvarezDepartment of Clinical Microbiology, Instituto de Investigación Sanitaria Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
María José ValderramaDepartment of Genetics, Physiology and Microbiology, Faculty of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Luis VallejoDepartment of Clinical Microbiology, Instituto de Investigación Sanitaria Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Alberto Delgado-IribarrenDepartment of Medicine, Facultad de Medicina, Universidad Complutense Madrid, Plaza Ramón y Cajal S/N, Madrid, 28040, Spain.
Esther CulebrasDepartment of Medicine, Facultad de Medicina, Universidad Complutense Madrid, Plaza Ramón y Cajal S/N, Madrid, 28040, Spain.
Universidad Complutense de Madrid · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ADVIA Centaur SARS-CoV-2 Antigen (COV2Ag) Assay (Siemens Healthineers) was evaluated for SARS-CoV-2 detection. A total of 141 nasopharyngeal samples were analyzed by this technique and results were compared with those obtained by quantitative reverse-transcription polymerase chain reaction (RT-PCR). The overall sensitivity and specificity of the test were 68.70% and 70%, respectively. Regarding cycle threshold (Ct) values, the COV2Ag test showed a sensitivity of 93.75% and 100% for nasopharyngeal samples with Ct < 25 and < 20, respectively. ADVIA Centaur COV2Ag Assay is a useful, automated, and rapid technique for early SARS-CoV-2 diagnosis and isolation of the infected individuals, avoiding its transmission.

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingHumansSerologic TestsViral LoadPCRRapid antigen testSARS-CoV-2SensitivitySpecificity

Identifiers

PMID36527576
PMCPMC9758452
OpenAlexW4312066728

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.