Evidence map›Paper›PMID 36527503›Full record

ArticleActa diabetologica2023

Heated tobacco product use and abnormal glucose metabolism: a working population-based study.

Huan Hu, Toshiaki Miyamoto, Hiroko Okazaki, Masafumi Eguchi, Taiki Shirasaka, Takeshi Kochi, Isamu Kabe, Aki Tomizawa, Tohru Nakagawa, Toru Honda and 9 more

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Article in Acta diabetologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Huan HuResearch Center for Prevention From Radiation Hazards of Workers, National Institute of Occupational Safety and Health, Nagao 6-21-1, Tama-Ku, Kawasaki, 214-8585, Japan. hu.huanhuan@yahoo.com.ORCID http://orcid.org/0000-0001-8558-2895
Toshiaki MiyamotoNippon Steel Corporation, East Nippon Works Kimitsu Area, Chiba, Japan.
Hiroko OkazakiMitsui Chemicals, Inc., Tokyo, Japan.
Masafumi EguchiFurukawa Electric Co., Ltd., Tokyo, Japan.
Taiki ShirasakaFurukawa Electric Co., Ltd., Tokyo, Japan.
Takeshi KochiFurukawa Electric Co., Ltd., Tokyo, Japan.
Isamu KabeKUBOTA Corporation Co., Ltd., Ibaraki, Japan.
Aki TomizawaHealth Design Inc., Tokyo, Japan.
Tohru NakagawaHitachi Health Care Center, Hitachi, Ltd., Ibaraki, Japan.
Toru HondaHitachi Health Care Center, Hitachi, Ltd., Ibaraki, Japan.
Shuichiro YamamotoHitachi Health Care Center, Hitachi, Ltd., Ibaraki, Japan.
Takako MikiDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Ami FukunagaDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Shohei YamamotoDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Yosuke InoueDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Haruka MiyakeDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Maki KonishiDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Seitaro DohiMitsui Chemicals, Inc., Tokyo, Japan.
Tetsuya MizoueDepartment of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.

Funding

Japan Society for the Promotion of Science 20H03952National Center for Global Health and Medicine 19A1006
6 · The paper itself

Abstract

aimsWe aimed to assess the cross-sectional association of heated tobacco product (HTP) use with prediabetes and diabetes.

methodsThe present analysis included 8950 workers from 5 companies (Study I) and 31,341 workers from another large company (Study II), who participated in the Japan Epidemiology Collaboration on Occupational Health Study. The participants were divided into five groups: never smokers, past smokers, exclusive HTP users, dual users of cigarettes and HTPs, and exclusive cigarette smokers. Diabetes and prediabetes were defined according to the fasting blood glucose and HbA1c levels and self-reported diabetes treatment, using the American Diabetes Association criteria. We analyzed the data of Study I and II separately, and then pooled these estimates using the fixed-effect models, with adjustment for a wide range of covariates.

resultsIn this study that included 40,291 participants (mean age, 46.6 years; men, 84.3%), about half of the current tobacco-related product users reported using HTPs. Exclusive HTP users had higher odds of prediabetes (pooled odds ratio 1.36; 95% CI 1.25-1.47) and diabetes (1.68; 95% CI 1.45-1.94) than never smokers. Similarly, dual users also had increased odds of prediabetes (pooled odds ratio, 1.26; 95% CI 1.13-1.39) and diabetes (1.93; 95% CI 1.63-2.29). The strength of these associations was comparable to that of cigarette smokers. We observed significantly higher HbA1c and fasting blood glucose levels among both exclusive HTP users and dual users compared to never smokers.

conclusionHTP use was associated with an increased likelihood of prediabetes and diabetes. Prospective studies are warranted to confirm the cross-sectional association.

Indexed as

Prediabetic StateTobacco ProductsBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedSurveys and QuestionnairesBlood GlucoseGlycated HemoglobinDiabetesHeated tobacco productPrediabetesSmoking

Identifiers

PMID36527503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.