Evidence map›Paper›PMID 36527471›Full record

ArticleWorld journal of urology2023

Post-voided residual urine ratio as a predictor of bladder outlet obstruction in men with lower urinary tract symptoms: development of a clinical nomogram.

Antonio Cicione, Riccardo Lombardo, Antonio Nacchia, Beatrice Turchi, Giacomo Gallo, Filippo Zammitti, Nicola Ghezzo, Alessio Guidotti, Antonio Franco, Lorenzo Maria Rovesti and 9 more

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Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Antonio CicioneDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Riccardo LombardoDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Antonio NacchiaDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Beatrice TurchiDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Giacomo GalloDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Filippo ZammittiDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Nicola GhezzoDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Alessio GuidottiDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Antonio FrancoDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Lorenzo Maria RovestiDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Carmen GravinaDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Elisa ManciniDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Sara RioloDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Antonio PastoreICOT Latina, Latina, Italy.
Giorgia TemaDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Simon CarterDepartment of Urology, London Clinic, London, UK.
Carlo VicentiniDepartment of Surgical Sciences, University of L'Aquila, L'Aquila, Italy.
Andrea TubaroDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy.
Cosimo De NunzioDepartment of Urology, Ospedale Sant'Andrea, La Sapienza University, Rome, Italy. cosimodenunzio@virgilio.it.ORCID http://orcid.org/0000-0002-2190-512X
Azienda Ospedaliera Sant'Andrea · ITLondon Clinic · GBUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo confirm the correlation between post-void residual urine ratio (PVR-R) and BOO diagnosed by pressure-flow studies (PFS) in males with lower urinary tract symptoms (LUTS) and to develop a clinical nomogram.

methodsA consecutive series of patients aged 45 years or older with non-neurogenic LUTS were prospectively enrolled. Patients underwent standard diagnostic assessment for BOO including International Prostatic Symptoms Score, uroflowmetry, urodynamic studies, suprapubic ultrasound of the prostate, and ultrasound measurements of the bladder wall thickness (BTW). PVR-R was defined as follows: PVR-R = (PVR/total Bladder Volume [BV]) × 100). Logistic regression analysis was used to investigate predictors of pathological bladder emptying (BOO) defined as Schafer > II. A nomogram to predict BOO based on the multivariable logistic regression model was then developed.

resultsOverall 335 patients were enrolled. Overall, 131/335 (40%) presented BOO on PFS. In a multivariable logistic age-adjusted regression model BWT (odds ratio [OR]: 2.21 per mm; 95% confidence interval [CI], 1.57-3.09; p = 0.001), PVR-R (OR: 1.02 per %; 95% CI, 1.01-1.03; p = 0.034) and prostate volume (OR: 0.97 per mL; 95% CI, 0.95-0.98; p = 0.001) were significant predictors for BOO. The model presented an accuracy of 0.82 and a clinical net benefit in the range of 10-90%.

conclusionsThe present study confirms the important role of PVR-ratio in the prediction of BOO. For the first time, we present a clinical nomogram including PVR-ratio for the prediction of BOO.

Indexed as

Lower Urinary Tract SymptomsProstatic HyperplasiaUrinary Bladder Neck ObstructionUrinary RetentionHumansMaleNomogramsUrodynamicsBOOLUTSNomogramPost-void residual urine

Identifiers

PMID36527471
OpenAlexW4311822104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.