ArticleSeminars in ophthalmology2023
Penetrating Keratoplasty: Indications and Graft Survival by Geographic Region.
Article in Seminars in ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Long-Term Graft Survival Following Penetrating Keratoplasty in Eyes with Preoperative Corneal Neovascularization.Ophthalmology and therapy · 2026Article
- CHARACTERISTICS AND VITREORETINAL MANAGEMENT OF RETINAL DETACHMENT IN EYES AFTER PENETRATING KERATOPLASTY IN a 10-YEAR STUDY.Retina (Philadelphia, Pa.) · 2026Article
- Amniotic membrane plugging versus acellular porcine corneal partially penetrating deep anterior lamellar keratoplasty in the treatment of small corneal perforation.Frontiers in medicine · 2026Article
- Corneal Myofibroblasts Suppress T-Cell Immunity in Corneal Transplantation.Investigative ophthalmology & visual science · 2025Article
- Anterior segment optical coherence tomography (AS-OCT) assisted analysis of characteristics of graft dehiscence after Descemet membrane endothelial keratoplasty (DMEK) for failed penetrating keratoplasty.Acta ophthalmologica · 2025Article
- Co-differentiation and enrichment of corneal endothelial cells and keratocytes from human pluripotent stem cells.Scientific reports · 2025Article
- Article
- Femtosecond-Laser-Assisted Liquid-Interface vs Vacuum-Trephine Keratoplasty: A Comparison of 2 Different Techniques - Retrospective Data Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Assessment of the Quality and Readability of Online Resources on Corneal Transplantation.Cureus · 2024Article
- Efficacy of Emergency Penetrating Keratoplasty with Cryopreserved Human Donor Corneas.Ophthalmology and therapy · 2024Article
- Views of admitted palliative care patients and their clinicians on corneal donation discussions: a qualitative content analysis of semi-structured interviews.BMC palliative care · 2024Article
- An Overview of Corneal Transplantation in the Past Decade.Clinics and practice · 2023Review
- Corneal blindness in the developing world: The role of prevention strategies.F1000Research · 2023Article
- Main issues in penetrating keratoplasty.Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Corneal transplantation, or penetrating keratoplasty (PK), is the most common form of solid-organ transplantation performed worldwide. Here, we evaluated the indications for PK and rates of transplant survival around the world by geographic region. We conducted a literature search of PubMed, MEDLINE, and Google Scholar databases and identified 155 relevant studies from 41 countries published between 1987 and 2021. The most common indications for PK were keratoconus in Europe, Africa, the Middle East, Australia, New Zealand, and Central and South America, bullous keratopathy in North America, and corneal scarring in Asia. The overall global mean graft survival rates at 1-, 2-, 3-, 5-, and 10-years were 88.6%, 81.2%, 78.9%, 72.8%, and 61.2%, respectively. Through this systematic analysis of PK by region, we hope to bring a new perspective to the corneal transplantation literature and to potentially highlight global differences and unmet needs in patient care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.