ArticleGeriatrics & gerontology international2023
Sarcopenia and decline in appendicular skeletal muscle mass are associated with hypoperfusion in key hubs of central autonomic network on 3DSRT in older adults with progression of normal cognition to Alzheimer's disease.
Article in Geriatrics & gerontology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Prevalence and correlation of sarcopenia with Alzheimer's disease: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Meta-analysis on the interrelationship between sarcopenia and mild cognitive impairment, Alzheimer's disease and other forms of dementia.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Sarcopenia in cognitive disorders: Toward a shared pathophysiological framework.Osteoporosis and sarcopenia · 2026Review
- Prevalence of low muscle mass and its association with orthostatic hypotension and related symptoms in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- The mediating effect of arteriosclerosis on the relationship between sarcopenia and cognitive impairment: a retrospective analysis.Frontiers in medicine · 2026Article
- The relationship between skeletal muscle mass and cognitive impairment in older adults: a longitudinal study based on CLHLS.Frontiers in public health · 2025Article
- The relationship between cognitive function and muscle mass in older adults: a longitudinal study based on CLHLS.Frontiers in psychiatry · 2025Article
- Alzheimer's Disease: Understanding Motor Impairments.Brain sciences · 2024Review
- Sarcopenia in subjects with Alzheimer's disease: prevalence and comparison of agreement between EGWSOP1, EGWSOP2, and FNIH criteria.BMC geriatrics · 2024Article
- Sarcopenia and decline in appendicular skeletal muscle mass are associated with hypoperfusion in key hubs of central autonomic network on 3DSRT in older adults with progression of normal cognition to Alzheimer's disease.Geriatrics & gerontology international · 2023Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
aimAlthough sarcopenia is common in patients with Alzheimer's disease (AD), the neural substrates involved remain unclear. We investigated the relationship between sarcopenia, as well as its definition components, and regional cerebral blood flow (rCBF) in older adults with progression of normal cognition to AD.
methods
resultsLogistic regression analysis adjusted by age, sex, mini-mental state examination score and education showed that sarcopenia as well as ASMI less than the cut-off (men 7.0 kg/m
conclusionsHypoperfusion in key hubs of central autonomic network is implicated in the emergence of sarcopenia, probably through ASMI decline in vulnerable older adults. Geriatr Gerontol Int 2023; 23: 16-24.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.