Evidence map›Paper›PMID 36526924›Full record

Trial reportApplied psychophysiology and biofeedback2023

For Which Children with ADHD is TBR Neurofeedback Effective? Comorbidity as a Moderator.

Michelle E Roley-Roberts, Xueliang Pan, Rachel Bergman, Yubo Tan, Kyle Hendrix, Roger deBeus, Cynthia Kerson, Martijn Arns, Nadja R Ging Jehli, Shea Connor and 2 more

Erratum issued Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Applied psychophysiology and biofeedback, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02251743 (Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02251743 nacompletednot on this map

Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD

TypeinterventionalSponsorOhio State UniversityRan2014 to 2020Enrolled144ConditionsAttention-Deficit/Hyperactivity DisorderArmsNeurofeedback treatment
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Michelle E Roley-Roberts *Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA. michelle.e.roley@gmail.com.ORCID 0000-0002-9269-418X
Xueliang Pan *Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-2342-3212
Rachel BergmanDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA.
Yubo TanDepartment of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-7495-5446
Kyle HendrixCollege of Medicine, The Ohio State University, Columbus, OH, USA.
Roger deBeusDepartment of Psychology, University of North Carolina at Asheville, Asheville, NC, USA.ORCID 0000-0001-9426-2690
Cynthia KersonDepartment of Applied Psychophysiology, Saybrook University, Pasadena, CA, USA.ORCID 0000-0001-5861-1443
Martijn ArnsResearch Institute Brainclinics, Nijmegen, The Netherlands.ORCID 0000-0002-0610-7613
Nadja R Ging JehliDepartment of Psychology, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-1071-0693
Shea ConnorDepartment of Psychology, University of North Carolina at Asheville, Asheville, NC, USA.
Constance SchraderDepartment of Psychology, University of North Carolina at Asheville, Asheville, NC, USA.
L Eugene ArnoldDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-0886-0692
The Ohio State University · USUniversity of North Carolina at Asheville · USCreighton University · USSaybrook University · USUtrecht University · NL

Funding

Double-Blind Randomized Clinical Trial of EEG Neurofeedback for ADHDR01MH100144 · NIMH · OHIO STATE UNIVERSITY · PI ARNOLD, L EUGENE · 2014 to 2018
$3.5M
NIMH NIH HHS R01 MH100144
6 · The paper itself

Abstract

We examined psychiatric comorbidities moderation of a 2-site double-blind randomized clinical trial of theta/beta-ratio (TBR) neurofeedback (NF) for attention deficit hyperactivity disorder (ADHD). Seven-to-ten-year-olds with ADHD received either NF (n = 84) or Control (n = 58) for 38 treatments. Outcome was change in parent-/teacher-rated inattention from baseline to end-of-treatment (acute effect), and 13-month-follow-up. Seventy percent had at least one comorbidity: oppositional defiant disorder (ODD) (50%), specific phobias (27%), generalized anxiety (23%), separation anxiety (16%). Comorbidities were grouped into anxiety alone (20%), ODD alone (23%), neither (30%), or both (27%). Comorbidity (p = 0.043) moderated acute effect; those with anxiety-alone responded better to Control than to TBR NF (d = - 0.79, CI - 1.55- - 0.04), and the other groups showed a slightly better response to TBR NF than to Control (d = 0.22 ~ 0.31, CI - 0.3-0.98). At 13-months, ODD-alone group responded better to NF than Control (d = 0.74, CI 0.05-1.43). TBR NF is not indicated for ADHD with comorbid anxiety but may benefit ADHD with ODD.Clinical Trials Identifier: NCT02251743, date of registration: 09/17/2014.

Indexed as

Attention Deficit Disorder with HyperactivityNeurofeedbackAnxiety DisordersAttention Deficit and Disruptive Behavior DisordersChildComorbidityHumansADHDComorbidityElectroencephalography (EEG)RCT design

Identifiers

PMID36526924
OpenAlexW4311692290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.