Evidence map›Paper›PMID 36526871›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

The effects of myofascial induction therapy in survivors of head and neck cancer: a randomized, controlled clinical trial.

Lucía Ortiz-Comino, Lydia Martín-Martín, Noelia Galiano-Castillo, Eduardo Castro-Martín, Miguel Ángel Fernández-Gualda, Mario Lozano-Lozano, Carolina Fernández-Lao

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06148077 (Effects of Manual Therapy on Oral Opening, Swallow Function, and Upper Quarter Mobility in Chilean Survivors of Head and Neck Cancer), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06148077 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Manual Therapy on Oral Opening, Swallow Function, and Upper Quarter Mobility in Chilean Survivors of Head and Neck Cancer: A Study Protocol for a Controlled, Randomized Study (MATEO Study, MAnual ThErapy for Oral Opening).

TypeinterventionalSponsorUniversidad de La FronteraRan2024 to 2025Enrolled70ConditionsHead and Neck Cancer, Trismus, DysfunctionArmsManual Therapy, Motor control exercises
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury?Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
  2. Review
  3. Chronic Pain in the Cancer Survivor.Current pain and headache reports · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lucía Ortiz-CominoDepartment of Physical Therapy. Health Sciences Faculty, University of Granada, Melilla, Spain.
Lydia Martín-MartínDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain. lydia@ugr.es.
Noelia Galiano-CastilloDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
Eduardo Castro-MartínDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
Miguel Ángel Fernández-GualdaDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
Mario Lozano-LozanoDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
Carolina Fernández-LaoDepartment of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aim to evaluate the effects of myofascial induction therapy (MIT) on the sequelae suffered by the survivors of HNC (sHNC).

methodsWe enrolled 46 sHNC in a randomized controlled trial (RCT), of whom 20 received a MIT protocol and 23 were placed on a waitlist while receiving the recommended treatment for 6 weeks. The MIT protocol included a total of 18 sessions, 3 days a week on alternate days for 6 weeks. Maximal mouth opening, the presence of temporomandibular dysfunction, cervical endurance, active range of motion (AROM), shoulder AROM, handgrip strength, and perceived physical fitness were assessed.

resultsMaximal mouth opening, temporomandibular dysfunction, cervical endurance, and AROM, affected shoulder abduction and unaffected shoulder flexion and external rotation significantly improved (p < .05) after an MIT protocol, but only cervical AROM and affected shoulder abduction changes were clinically meaningful. No statistically significant changes were observed in the other shoulder AROM, handgrip strength, or physical fitness perception (p > .05).

conclusionA 6-week MIT protocol improves mouth opening, TMD, cervical function (endurance and AROM), affected shoulder abduction and unaffected shoulder flexion, and external rotation AROM in the sHNC. However, no changes were observed in most of the shoulder AROM, muscular strength, or perceived physical fitness. Future studies should perform longer follow-up designs, increase the sample size, and include multimodal treatments to address these sequelae in the sHNC.

Indexed as

Head and Neck NeoplasmsInduction ChemotherapyHumansRange of Motion, ArticularShoulderSurvivorsHead and neck cancerManual therapyMusculoskeletal manipulationsRandomized controlled trialRange of motionSurvivors

Identifiers

PMID36526871
PMCPMC9758021
OpenAlexW4312065691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.