ReviewBritish dental journal2022
Minimally invasive endodontics: a new era for pulpotomy in mature permanent teeth.
Review in British dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Partial pulpotomy for carious pulp exposure in adult mature permanent teeth: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Clinical and radiographic outcomes of pulpotomy materials in permanent teeth: a systematic review of calcium hydroxide, MTA, biodentine, and iRoot BP plus.BMC oral health · 2025Pooled it
- Twenty-four-month outcomes of full pulpotomy in permanent molars with symptomatic irreversible pulpitis: a randomized controlled trial of adjunctive cryotherapy.Clinical oral investigations · 2026Trial
- Postoperative pain after pulpotomy versus pulpectomy of primary molars with symptomatic irreversible pulpitis: an equivalent randomized clinical trial.BMC oral health · 2026Trial
- Full pulpotomy versus root canal therapy in mature teeth with irreversible pulpitis: a randomized controlled trial.BMC oral health · 2024Trial
- The effect of two different contemporary chelating agents on vital pulp therapy in mature permanent teeth with irreversible pulpitis using bioceramic material: randomized clinical trial.BMC oral health · 2024Trial
- Pulpotomy versus pulpectomy in carious vital pulp exposure in primary incisors: a randomized controlled trial.BMC oral health · 2024Trial
- The effect of calcium hydroxide and double antibiotic paste on radiographic outcomes and periapical MMP-8 levels in regenerative endodontic procedures: a randomized clinical trial.Journal of applied oral science : revista FOB · 2024Trial
- Establishment of an MRI-Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries-Derived Pulpitis Model.International endodontic journal · 2026Article
- Review
- Decision-ready evidence for vital pulp therapy: a network meta-analysis of bioactive materials in mature permanent teeth.Frontiers in dental medicine · 2026Review
- CBCT-Assisted Microsurgical Management of Dual Periapical Lesions Involving Vital and Previously Endodontically Treated Maxillary Molars: A Case Report.Clinical case reports · 2026Article
- Diagnosis to Follow-Up: Practice Variability and Evidence-Based Gaps In Vital Pulp Therapy Among Saudi Dentists.Oral health & preventive dentistry · 2025Article
- In Vivo Comparison of Resin-Modified and Pure Calcium-Silicate Cements for Direct Pulp Capping.Applied sciences (Basel, Switzerland) · 2025Article
- Outcome of full pulpotomy versus partial radicular pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis using Biodentine - A randomized controlled trial.Journal of conservative dentistry and endodontics · 2025Article
- Role of Dystrophic Calcification in Reparative Dentinogenesis After Rat Molar Pulpotomy.International journal of molecular sciences · 2025Article
- Comparative Evaluation of Three Calcium Silicate-Based Materials for Direct Pulp Capping: AnbioRxiv : the preprint server for biology · 2025Article
- The effect of age and preoperative diagnosis on the outcome of partial and cervical pulpotomies in immature permanent teeth.Clinical oral investigations · 2025Article
- Expert consensus on pulpotomy in the management of mature permanent teeth with pulpitis.International journal of oral science · 2025Review
- Artificial intelligence-produced radiographic enhancements in dental clinical care: provider and patient perspectives.Frontiers in oral health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging clinical and histologic evidence is challenging the long-established dogma that root canal treatment (RCTx) is the only therapeutic option for preservation of vital mature permanent teeth diagnosed with irreversible pulpitis or carious pulp exposure. Vital pulp therapy procedures like pulpotomy are not only technically simpler and more economical, but also afford patients a host of other benefits over conventional RCTx. This narrative review provides an update on the contemporary understanding of pulp pathophysiology and defence mechanisms, the proposed new diagnostic terminologies for pulpal inflammation, and how the biological characteristics of hydrophilic calcium silicate cements have enabled consistent successful outcomes for pulpotomy-treated mature teeth. The paper also details the evidence base from clinical trials and systematic reviews conducted over the past decade and outlines the practical treatment considerations for pulpotomy in mature permanent teeth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.