Evidence map›Paper›PMID 36526365›Full record

ArticleeNeuro2023

Comparative Proteomics Analysis of Growth-Primed Adult Dorsal Root Ganglia Reveals Key Molecular Mediators for Peripheral Nerve Regeneration.

Maricris Bautista, George S Katselis, Bari Chowdhury, Paulos Chumala, Ruhi Mahendra, Priyanshi Desai, Justin Hall, Subha Kalyaanamoorthy, Anand Krishnan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maricris BautistaDepartment of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
George S KatselisCanadian Centre for Health and Safety in Agriculture (CCHSA), Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 2Z4, Canada.
Bari ChowdhuryDepartment of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Paulos ChumalaCanadian Centre for Health and Safety in Agriculture (CCHSA), Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 2Z4, Canada.
Ruhi MahendraDepartment of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Priyanshi DesaiDepartment of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Justin HallDepartment of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Subha KalyaanamoorthyDepartment of Chemistry, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Anand KrishnanDepartment of Anatomy, Physiology, and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada anand.krishnan@usask.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injuries to peripheral nerves are frequent, yet no drug therapies are available for effective nerve repair. The slow growth rate of axons and inadequate access to growth factors challenge natural repair of nerves. A better understanding of the molecules that can promote the rate of axon growth may reveal therapeutic opportunities. Molecular profiling of injured neurons at early intervals of injury, when regeneration is at the maximum, has been the gold standard for exploring growth promoters. A complementary

Indexed as

Ganglia, SpinalPeripheral Nerve InjuriesAnimalsAxonsCells, CulturedNerve RegenerationProteomicsRatsRats, Sprague-DawleySensory Receptor Cellsdorsal root gangliaMANFneurite outgrowthperipheral nerve injuryprimingproteomics

Identifiers

PMID36526365
PMCPMC9829101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.