Evidence map›Paper›PMID 36526320›Full record

Trial reportBMJ open2022

Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial.

Prathiba Chitsabesan, Charlotte Lucy Hall, Lesley-Anne Carter, Mindy Reeves, Vaseem Mohammed, Bryony Beresford, Susan Young, Abdullah Kraam, Sally Trowse, Lloyd Wilkinson-Cunningham and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Prathiba ChitsabesanChildren and Young People's Research Unit, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UK pchitsabesan@nhs.net.ORCID 0000-0002-0968-3472
Charlotte Lucy HallPsychiatry, Institute of Mental Health, NIHR CLAHRC-East Midlands, Nottingham, UK.ORCID 0000-0002-5412-6165
Lesley-Anne CarterCentre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Manchester, UK.
Mindy ReevesMedical School, The University of Manchester, Manchester, UK.
Vaseem MohammedMedical School, The University of Manchester, Manchester, UK.
Bryony BeresfordSocial Policy Research Unit, University of York, York, UK.
Susan YoungDepartment of Clinical and Forensic Psychology, Psychology ServicesLimited, London, UK.
Abdullah KraamChildren and Adolescent Mental Health, Rotherham Doncaster and South Humber Mental Health NHS Foundation Trust, Doncaster, UK.
Sally TrowseChild and Adolescent Mental Health Service, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UK.
Lloyd Wilkinson-CunninghamResearch andDevelopment, Leeds Community Healthcare NHS Trust, Leeds, UK.
Charlotte LennoxManchester Academic Health Science Centre, University of Manchester, Manchester, UK.ORCID 0000-0001-9014-9965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesQbTest has been shown to improve time to decision/diagnosis for young people with attention deficit hyperactivity disorder (ADHD). The aim was to assess the feasibility of QbTest for young people in prison.

designSingle-centre feasibility randomised controlled trial (RCT), with 1:1 allocation. Concealed random allocation using an online pseudorandom list with random permuted blocks of varying sizes.

settingOne Young Offenders Institution in England.

participants355 young people aged 15-18 years displaying possible symptoms of ADHD were assessed for eligibility, 69 were eligible to take part and 60 were randomised.

interventionQbTest-a computer task measuring attention, activity and impulsivity.

main outcome measuresEligibility, recruitment and retention rates and acceptability of randomisation and trial participation.

resultsOf the 355 young people assessed for eligibility, 69 were eligible and 60 were randomised (n=30 QbTest plus usual care; n=30 usual care alone). The study achieved the specified recruitment target. Trial participation and randomisation were deemed acceptable by the majority of participants. 78% of young people were followed up at 3 months, but only 32% at 6 months, although this was also affected by COVID-19 restrictions. Secondary outcomes were mixed. Participants including clinical staff were mostly supportive of the study and QbTest; however, some young people found QbTest hard and there were issues with implementation of the ADHD care pathway. There were no serious adverse events secondary to the study or intervention and no one was withdrawn from the study due to an adverse event.

conclusionsWith adaptations, a fully powered RCT may be achievable to evaluate the effectiveness of QbTest in the assessment of ADHD in the Children and Young People Secure Estate, with time to decision (days) as the primary outcome measure. However, further programme developmental work is required to address some of the challenges highlighted prior to a larger trial. TRIAL REGISTRATION NUMBER: ISRCTN17402196.

Indexed as

Attention Deficit Disorder with HyperactivityCOVID-19AdolescentChildComputersFeasibility StudiesHumansImpulsive BehaviorChild & adolescent psychiatryDevelopmental neurology & neurodisabilityMENTAL HEALTH

Identifiers

PMID36526320
PMCPMC9764651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.