Evidence map›Paper›PMID 36526234›Full record

ReviewInternational journal of radiation oncology, biology, physics2023

Increasing Diversity of Patients in Radiation Oncology Clinical Trials.

Emily Roy, Fumiko Chino, Benjamin King, Chika Madu, Malcolm Mattes, Rosalyn Morrell, Julianne Pollard-Larkin, Malika Siker, Christiane Takita, Michelle Ludwig

Open access · greenAbstract readReview
In one paragraph

Review in International journal of radiation oncology, biology, physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Emily RoyBaylor College of Medicine, Houston, Texas.
Fumiko ChinoDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Benjamin KingDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, California.
Chika MaduDepartment of Radiation Oncology, Staten Island University Hospital, Staten Island, New York.
Malcolm MattesDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
Rosalyn MorrellAdvanced Radiation Center of Beverly Hills, Beverly Hills, California.
Julianne Pollard-LarkinDepartment of Radiation Physics, MD Anderson Cancer Center, Houston, Texas.
Malika SikerDepartment of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Christiane TakitaDepartment of Radiation Oncology, Miami University School of Medicine, Miami, Florida.
Michelle LudwigDepartment of Radiation Oncology, Baylor College of Medicine, Houston, Texas. Electronic address: michelle.ludwig@bcm.edu.
Baylor College of Medicine · USCedars-Sinai Medical Center · USMemorial Sloan Kettering Cancer Center · USRutgers Cancer Institute of New JerseyStaten Island University Hospital · USThe University of Texas MD Anderson Cancer Center · USUniversity of Miami · USUniversity of Wisconsin–Madison · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Radiation oncology clinical trials lack full representation of the ethnic and racial diversity present in the general United States and in the cancer patient population. There are low rates of both recruitment and enrollment of individuals from underrepresented ethnic and racial backgrounds, especially Black and Hispanic patients, people with disabilities, and patients from underrepresented sexual and gender groups. Even if approached for enrollment, barriers such as mistrust in medical research stemming from historical abuse and contemporary biased systems, low socioeconomic status, and lack of awareness prohibit historically marginalized populations from participating in clinical trials. In this review, we reflect on these specific barriers and detail approaches to increase diversity of the patient population in radiation oncology clinical trials to better reflect the communities we serve. We hope that implementation of these approaches will increase the diversity of clinical trials patient populations in not only radiation oncology but also other medical specialties.

Indexed as

Clinical Trials as TopicCultural DiversityNeoplasmsRadiation OncologyBlack or African AmericanHispanic or LatinoHumansMinority GroupsRacial GroupsUnited States

Identifiers

PMID36526234
PMCPMC10414211
OpenAlexW4311823773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.