Evidence map›Paper›PMID 36525845›Full record

ArticleMedical image analysis2023

Co-attention spatial transformer network for unsupervised motion tracking and cardiac strain analysis in 3D echocardiography.

Shawn S Ahn, Kevinminh Ta, Stephanie L Thorn, John A Onofrey, Inga H Melvinsdottir, Supum Lee, Jonathan Langdon, Albert J Sinusas, James S Duncan

Open access · greenAbstract read
In one paragraph

Article in Medical image analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Ultrasound Image Analysis with Vision Transformers-Review.Diagnostics (Basel, Switzerland) · 2024
    Review
  7. Cross-Attention for Improved Motion Correction in Brain PET.Machine learning in clinical neuroimaging : 6th international workshop, MLCN 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, proceedings. MLCN (Workshop) (6th : 2023 : Vancouver, B.C.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shawn S AhnDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA. Electronic address: shawn.ahn@yale.edu.
Kevinminh TaDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA.
Stephanie L ThornSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA.
John A OnofreyDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA; Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Inga H MelvinsdottirSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA.
Supum LeeSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA.
Jonathan LangdonDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Albert J SinusasDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA; Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
James S DuncanDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA; Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA; Department of Electrical Engineering, Yale University, New Haven, CT, USA. Electronic address: james.duncan@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Medical Scientist Training ProgramT32GM136651 · NIGMS · YALE UNIVERSITY · PI BARBARA I KAZMIERCZAK · 2020 to 2026
$16.5M
q4DE: A Biomarker for Image-Guided, Post-MI Hydrogel TherapyR01HL121226 · NHLBI · YALE UNIVERSITY · PI DUNCAN, JAMES S, O'DONNELL, MATTHEW · 2014 to 2022
$6.3M
Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Image Guided Delivery of Bioresponsive HydrogelsR01HL137365 · NHLBI · YALE UNIVERSITY · PI BURDICK, JASON A, DUNCAN, JAMES S · 2018 to 2021
$3.2M
Ultrasound System for Transational ResearchS10OD028738 · OD · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2021 to 2021
$590k
Hybrid Volumetric SPECT/CT Imaging SystemS10RR025555 · NCRR · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2009 to 2009
$500k
Deep Learning-based Framework for Segmentation and Motion Tracking of Left Ventricle in 3D EchocardiographyF30HL158154 · NHLBI · YALE UNIVERSITY · PI AHN, SHAWN · 2021 to 2023
$113k
NCATS NIH HHS UL1 TR001863NCRR NIH HHS S10 RR025555NHLBI NIH HHS F30 HL158154NHLBI NIH HHS R01 HL121226NHLBI NIH HHS R01 HL137365NHLBI NIH HHS T32 HL098069NIGMS NIH HHS T32 GM007205NIGMS NIH HHS T32 GM136651NIH HHS S10 OD028738
6 · The paper itself

Abstract

Myocardial ischemia/infarction causes wall-motion abnormalities in the left ventricle. Therefore, reliable motion estimation and strain analysis using 3D+time echocardiography for localization and characterization of myocardial injury is valuable for early detection and targeted interventions. Previous unsupervised cardiac motion tracking methods rely on heavily-weighted regularization functions to smooth out the noisy displacement fields in echocardiography. In this work, we present a Co-Attention Spatial Transformer Network (STN) for improved motion tracking and strain analysis in 3D echocardiography. Co-Attention STN aims to extract inter-frame dependent features between frames to improve the motion tracking in otherwise noisy 3D echocardiography images. We also propose a novel temporal constraint to further regularize the motion field to produce smooth and realistic cardiac displacement paths over time without prior assumptions on cardiac motion. Our experimental results on both synthetic and in vivo 3D echocardiography datasets demonstrate that our Co-Attention STN provides superior performance compared to existing methods. Strain analysis from Co-Attention STNs also correspond well with the matched SPECT perfusion maps, demonstrating the clinical utility for using 3D echocardiography for infarct localization.

Indexed as

Echocardiography, Three-DimensionalMyocardial InfarctionVentricular Dysfunction, LeftEchocardiographyHeartHumansEchocardiographySpatiotemporal attentionUnsupervised motion tracking

Identifiers

PMID36525845
PMCPMC9812938
OpenAlexW4311492932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.