Evidence map›Paper›PMID 36525646›Full record

ArticleJournal of natural products2023

Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from

Sanjeevan Rajendran, Blazej Slazak, Supun Mohotti, Taj Muhammad, Adam A Strömstedt, Małgorzata Kapusta, Emilia Wilmowicz, Ulf Göransson, Chamari M Hettiarachchi, Sunithi Gunasekera

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  6. Protein and peptide letters · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Sanjeevan RajendranPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.ORCID 0000-0002-7351-805X
Blazej SlazakPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.
Supun MohottiDepartment of Chemistry, Faculty of Science, University of Colombo, Thurstan Road, Colombo 00300, Sri Lanka.
Taj MuhammadPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.
Adam A StrömstedtPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.
Małgorzata KapustaDepartment of Plant Cytology and Embryology, Faculty of Biology, University of Gdańsk, 59 Wita Stwosza, 80-308 Gdańsk, Poland.
Emilia WilmowiczFaculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 1 Lwowska Street, 87-100 Toruń, Poland.
Ulf GöranssonPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.
Chamari M HettiarachchiDepartment of Chemistry, Faculty of Science, University of Colombo, Thurstan Road, Colombo 00300, Sri Lanka.
Sunithi GunasekeraPhamacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, SE 75124 Uppsala, Sweden.ORCID 0000-0002-1089-4015
Uppsala University · SEUniversity of Colombo · LKNicolaus Copernicus University · PLUniversity of Gdańsk · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclotides are an intriguing class of structurally stable circular miniproteins of plant origin with numerous potential pharmaceutical and agricultural applications. To investigate the occurrence of cyclotides in Sri Lankan flora, 50 medicinal plants were screened, leading to the identification of a suite of new cyclotides from

Indexed as

CyclotidesPlants, MedicinalRubiaceaeAmino Acid SequencePlant ProteinsSri LankaCyclotidesgere 1 cyclotidePlant Proteins

Identifiers

PMID36525646
PMCPMC9887600
OpenAlexW4311825431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.