Evidence map›Paper›PMID 36525612›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2023

Survival in Young Adults With Cancer Is Associated With Medicaid Expansion Through the Affordable Care Act.

Xu Ji, Kewei Sylvia Shi, Ann C Mertens, Jingxuan Zhao, K Robin Yabroff, Sharon M Castellino, Xuesong Han

Abstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Impact of Social Determinants on Healthcare Transition Readiness Among Adolescent and Young Adult Childhood Cancer Survivors: A Mixed Methods Systematic Review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  4. Sociodemographic disparities and reasons for delayed healthcare among U.S. cancer survivors: an All of Us study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xu JiDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0003-3025-3984
Kewei Sylvia ShiSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA.ORCID 0000-0002-0024-4916
Ann C MertensDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.
Jingxuan ZhaoSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA.ORCID 0000-0002-2733-2000
K Robin YabroffSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA.ORCID 0000-0003-0644-5572
Sharon M CastellinoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA.
Xuesong HanSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA.ORCID 0000-0001-7159-7949

Funding

Understanding the impact of the Affordable Care Act on healthcare coverage, utilization, and outcomes for childhood cancer survivorsR03CA267456 · NCI · EMORY UNIVERSITY · PI JI, XU · 2022 to 2023
$170k
Understanding the impact of the Affordable Care Act on cancer treatment and outcomes for adolescents and young adults (AYA)R03CA259665 · NCI · EMORY UNIVERSITY · PI CASTELLINO, SHARON MARIE, JI, XU · 2021 to 2022
$158k
NCI NIH HHS R03 CA259665NCI NIH HHS R03 CA267456
6 · The paper itself

Abstract

purposeMedicaid expansion through the Affordable Care Act (ACA) has been shown to improve insurance coverage and early diagnosis of cancer in young adults (YAs); whether these improvements translate to survival benefits remains unknown. We examined the association between Medicaid expansion under the ACA and 2-year overall survival among YAs with cancer.

methodsUsing the National Cancer Database, we identified 345,413 YAs (age 18-39 years) diagnosed with cancer in 2010-2017. We applied the difference-in-differences (DD) method to estimate changes in 2-year overall survival after versus before Medicaid expansion in expansion versus nonexpansion states.

resultsAmong all YAs, 2-year overall survival increased more in expansion states (90.39% pre-expansion to 91.85% postexpansion) than in nonexpansion states (88.98% pre-expansion to 90.07% postexpansion), resulting in a net increase of 0.55 percentage points (ppt; 95% CI, 0.13 to 0.96). The expansion-associated survival benefit was concentrated in patients with female breast cancer (DD, 1.20 ppt; 95%CI, 0.27 to 2.12) when stratifying by cancer type and in patients with stage IV disease (DD, 2.56; 95%CI, 0.36 to 4.77) when stratifying by stage. In addition, greater survival benefit associated with Medicaid expansion was observed among racial and ethnic minoritized groups (DD, 1.01 ppt; 95% CI, 0.14 to 1.87) as compared with non-Hispanic White peers (DD, 0.41 ppt; 95% CI, -0.06 to 0.87) and among patients with a Charlson comorbidity score of ≥ 2 (DD, 6.48 ppt; 95% CI, 0.81 to 12.16) than those with a comorbidity score of 0 (DD, 0.44 ppt; 95% CI, 0.005 to 0.87).

conclusionMedicaid expansion under the ACA was associated with an improvement in overall survival among YAs with cancer, with survival benefits most pronounced among patients of under-represented race and ethnicity and patients with high-risk diseases.

Indexed as

Breast NeoplasmsMedicaidAdolescentAdultEthnicityFemaleHumansInsurance CoveragePatient Protection and Affordable Care ActUnited StatesYoung Adult

Identifiers

PMID36525612
PMCPMC10082236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.