Evidence map›Paper›PMID 36525481›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Acute sedentary behavior and cardiovascular disease research: standardizing the methodological posture.

Craig Paterson, Simon Higgins, Merilin Sikk, Keeron Stone, Simon Fryer, Lee Stoner

Open access · greenAbstract readEditorial
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Exercise snacks and physical fitness in sedentary populations.Sports medicine and health science · 2025
    Review
  4. Article
  5. The heart-bone connection: relationships between myocardial infarction and osteoporotic fracture.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  6. Review
  7. Article
  8. Improving rigor and reproducibility in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  9. Reply to Liu et al.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Craig PatersonDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0003-3125-9712
Simon HigginsDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Merilin SikkDepartment of Sport, Hartpury University, Hartpury, United Kingdom.
Keeron StoneCardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom.
Simon FryerSchool of Natural, Social, and Sport Sciences, University of Gloucestershire, Gloucester, United Kingdom.
Lee StonerDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-0682-2270
University of North Carolina at Chapel Hill · USCardiff Metropolitan University · GBHartpury University · GBUniversity of Gloucestershire · GB

Funding

Sitting Interruption and Whole-body Cardiovascular Health: Linking Physiological Responses to Risk BehaviorsR01HL157187 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HANSON, ERIK D · 2022 to 2025
$2.5M
Cardiometabolic Disease Prevention in College-based Young Adults: Mapping a Contextual Sedentary Behavior InterventionR01HL162805 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HANSON, ERIK D · 2022 to 2025
$2.2M
NHLBI NIH HHS R01 HL157187NHLBI NIH HHS R01 HL162805
6 · The paper itself

Abstract

Sedentary behavior has been identified as an independent predictor of future cardiovascular disease risk and all-cause mortality. To explain this association, a growing body of literature has sought to investigate the physiological underpinnings of this association with the goal of developing a biologically plausible model. In time, this biologically plausible model can be tested, and effective, translatable public health guidelines can be developed. However, to ensure that evidence across studies can be effectively synthesized, it is necessary to ensure their congruency and comparability. Although there are several key factors that should be considered and controlled across prolonged sitting studies, one pertinent issue is that of participant posture. There is currently a discourse within the literature regarding the posture that cardiovascular assessments are performed in and rest periods between posture transitions and subsequent measures. This perspectives piece makes the case for standardizing approaches across the research area and offers practical recommendations for future work.

Indexed as

Cardiovascular DiseasesSedentary BehaviorHumansPostureSitting PositionTime Factorscardiovascularmeasurementpostureprolonged sittingsedentary behavior

Identifiers

PMID36525481
PMCPMC9829480
OpenAlexW4311822239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.