ArticleEJNMMI physics2022
Evaluation of the performance of a high-resolution time-of-flight PET system dedicated to the head and breast according to NEMA NU 2-2012 standard.
Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Design and imaging performance of BPET-DBT - a dedicated scanner for breast imaging.Medical physics · 2026Article
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- Deep learning-based restoration of PET images from a dual-panel breast dedicated scanner.Zeitschrift fur medizinische Physik · 2026Article
- Beyond CT: Attenuation correction for stand-alone brain PET.Zeitschrift fur medizinische Physik · 2026Review
- Comparison of image quality of breast-specific positron emission tomography between opposite-type and ring-shaped systems: insights from Phantom and clinical studies in a Japanese multicenter trial.Annals of nuclear medicine · 2026Article
- Off-target binding ofAnnals of nuclear medicine · 2026Article
- Impact ofEJNMMI physics · 2025Article
- Optimizing LM-DRAMA parameters and non-local means filtering to improve small-lesion detectability in SiPM-based TOF breast PET.Physical and engineering sciences in medicine · 2025Article
- Crossover evaluation of time-of-flight-based attenuation correction in brainAnnals of nuclear medicine · 2025Article
- PICASSO: a universal brain phantom for positron emission tomography based on the activity painting technique.Physics in medicine and biology · 2024Article
- Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- Generating PET Attenuation Maps via Sim2Real Deep Learning-Based Tissue Composition Estimation Combined with MLACF.Journal of imaging informatics in medicine · 2024Article
- Repurposing iron chelators for accurate positron emission tomography imaging tracking of radiometal-labeled cell transplants.MedComm · 2024Article
- Image quality evaluation for a clinical organ-targeted PET camera.Frontiers in oncology · 2024Article
- The quest for multifunctional and dedicated PET instrumentation with irregular geometries.Annals of nuclear medicine · 2024Review
- Advances in Breast PET Instrumentation.PET clinics · 2024Review
- Organ-Specific Positron Emission Tomography Scanners for Breast Imaging: Comparison between the Performances of Prior and Novel Models.Diagnostics (Basel, Switzerland) · 2023Article
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11 authors.
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Abstract
backgroundThis study evaluated the physical performance of a positron emission tomography (PET) system dedicated to the head and breast according to the National Electrical Manufacturers Association (NEMA) NU2-2012 standard.
methodsThe spatial resolution, sensitivity, scatter fraction, count rate characteristics, corrections for count losses and randoms, and image quality of the system were determined. All measurements were performed according to the NEMA NU2-2012 acquisition protocols, but image quality was assessed using a brain-sized phantom. Furthermore, scans of the three-dimensional (3D) Hoffmann brain phantom and mini-Derenzo phantom were acquired to allow visual evaluation of the imaging performance for small structures.
resultsThe tangential, radial, and axial full width at half maximum (FWHM) at a 10-mm offset in half the axial field of view were measured as 2.3, 2.5, and 2.9 mm, respectively. The average system sensitivity at the center of the field of view and at a 10-cm radial offset was 7.18 and 8.65 cps/kBq, respectively. The peak noise-equivalent counting rate was 35.2 kcps at 4.8 kBq/ml. The corresponding scatter fraction at the peak noise-equivalent counting rate was 46.8%. The peak true rate and scatter fraction at 8.6 kBq/ml were 127.8 kcps and 54.3%, respectively. The percent contrast value for a 10-mm sphere was approximately 50%. On the 3D Hoffman brain phantom image, the structures of the thin layers composing the phantom were visualized on the sagittal and coronal images. On the mini-Derenzo phantom, each of the 1.6-mm rods was clearly visualized.
conclusionTaken together, these results indicate that the head- and breast-dedicated PET system has high resolution and is well suited for clinical PET imaging.
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