Evidence map›Paper›PMID 36525069›Full record

Trial reportJournal of cancer research and clinical oncology2023

Impact of physical activity on postural stability and coordination in children with posterior fossa tumor: randomized control phase III trial.

Mahmoud Usama, Faten Abdelaziem, Wafaa M Rashed, Eslam Maher, Mohamed El Beltagy, Wael Zekri

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled TrialClinical Trial, Phase III
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04528316 (Impact of Physical Activity on Postural Stability and Coordination in Children With Posterior Fossa Tumor), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04528316 nacompletednot on this map

Impact of Physical Activity on Postural Stability and Coordination in Children With Posterior Fossa Tumor

TypeinterventionalSponsorChildren's Cancer Hospital Egypt 57357Ran2020 to 2021Enrolled60ConditionsPosterior Fossa Tumor, Medulloblastoma, ChildhoodArmsPilates Core Stability Exercises program, Balance Program, Coordination
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mahmoud UsamaDepartment of Physical Therapy for Paediatrics, Faculty of Physical Therapy, Cairo University, 7 Ahmed Elzaiat St. Ben Elsaryat, El Dokki, Giza, Egypt. mahmoud_usama@cu.edu.eg.ORCID http://orcid.org/0000-0001-7787-1769
Faten AbdelaziemDepartment of Physical Therapy for Paediatrics, Faculty of Physical Therapy, Cairo University, 7 Ahmed Elzaiat St. Ben Elsaryat, El Dokki, Giza, Egypt.
Wafaa M RashedResearch Department, Children's Cancer Hospital Egypt 57357, Cairo, Egypt.
Eslam MaherResearch Department, Children's Cancer Hospital Egypt 57357, Cairo, Egypt.
Mohamed El BeltagyNeurosurgery Department, Kasr Al-Ainy School of Medicine, Cairo University, Giza, Egypt.
Wael ZekriPediatric Oncology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Cairo University · EGChildren Cancer Hospital · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPosterior fossa tumor is a type of brain tumor that is located at the borders of both the brain stem and cerebellum. The cerebellum is the brain region in charge of balance and coordination. Pediatric patients diagnosed with posterior fossa tumor have been reported to fall frequently.

objectivesThe aim of this study is to investigate the effectiveness of balance and coordination training in these children.

methodsThis randomized control clinical trial (ClinicalTrials.gov Identifier: NCT04528316) was carried out between September 2020 and April 2021 at Children's Cancer Hospital-57357. The inclusion criteria were patients with posterior fossa tumor in maintenance phase and, age between 5 and 12 years. The exclusion criteria were patients who had a genetic disorder or suffer from mental retardation, a chronic lung disease, severe cardiomyopathy, or a neuromuscular disease that does not relate to tumor. The study participants were randomly assigned into three groups: Group I/Control group: they received Pilates core stability exercises program, Group II/Postural stability group: they received the same program plus HUMAC balance program, and Group III/Coordination group: they received the same program plus coordination exercises of BOT-2. The semi-parametric proportional odds model was used to compare follow-up scores of the Postural stability group vs Control, and Coordination group vs Control, while adjusting for baseline values. All tests were two sided, with alpha set to 0.05.

resultsSixty children including 38 boys and 22 girls were enrolled in this study. In all three groups, postural stability and coordination improved significantly in terms of modified clinical test of sensory integration of balance, center of pressure, limits of stability, bilateral coordination, and upper-limb coordination.

conclusionThe current study supports the value of adding postural stability and coordination training to the physiotherapy plan for children with posterior fossa tumor. TRIAL REGISTRATION NUMBER AND DATE OF REGISTRATION: ClinicalTrials.gov Identifier: NCT04528316 on August 27, 2020.

Indexed as

Brain NeoplasmsInfratentorial NeoplasmsChildChild, PreschoolExerciseExercise TherapyFemaleHumansMalePhysical Therapy ModalitiesBalanceBOT-2ChildrenCoordinationHUMACPosterior fossa tumorPostural stability

Identifiers

PMID36525069
PMCPMC10356666
OpenAlexW4311677944

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.