Evidence map›Paper›PMID 36525027›Full record

ArticleThe Journal of cell biology2023

Cilia bent out of shape over dysfunctional astrocyte mitochondria.

Rachel M Bear, Tamara Caspary

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. NEKL-4 regulates microtubule stability and mitochondrial health inbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Rachel M BearNeuroscience Graduate Program, Emory University, Atlanta, GA, USA.ORCID 0000-0003-3497-5255
Tamara CasparyDepartment of Human Genetics, Emory University, Atlanta, GA, USA.ORCID 0000-0002-6579-7589

Funding

Genetic Dissection of Signaling and CiliaR35GM122549 · NIGMS · EMORY UNIVERSITY · PI CASPARY, TAMARA J. · 2017 to 2021
$2.0M
The Novel Role of Cilia in Astrocyte SevelopmentF31NS125984 · NINDS · EMORY UNIVERSITY · PI BEAR, RACHEL MARIE · 2023 to 2025
$123k
NIGMS NIH HHS R35 GM122549NIH HHS R35 GM122549NINDS NIH HHS F31 NS125984
6 · The paper itself

Abstract

Mitochondrial dysfunction in astrocytes drives neurodegenerative brain pathology. In this issue, Ignatenko et al. (2022. J. Cell. Biol.https://doi.org/10.1083/jcb.202203019) discover a novel connection between cilia and mitochondria in astrocytes, whereby mitochondrial dysfunction leads to abnormal cilia structure and a motile cilia program.

Indexed as

AstrocytesCiliaMitochondria

Identifiers

PMID36525027
PMCPMC9764019

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.