Evidence map›Paper›PMID 36524941›Full record

ReviewJournal of the Chinese Medical Association : JCMA2023

The Omicron variant wave: Where are we now and what are the prospects?

Mong-Lien Wang, Yang Lin, Ju-Fen Hou, Yi-Ping Yang, Yueh Chien, Yi-Chen Sun, Kung-Hao Liang, De-Ming Yang, Tai-Jay Chang, Cheng-Hsien Wu and 2 more

Abstract readReview
In one paragraph

Review in Journal of the Chinese Medical Association : JCMA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mong-Lien WangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yang LinDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Ju-Fen HouDepartment of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yi-Ping YangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yueh ChienDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yi-Chen SunCollege of Medicine, Tzu-Chi University, Hualien, Taiwan, ROC.
Kung-Hao LiangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
De-Ming YangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Tai-Jay ChangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Cheng-Hsien WuDepartment of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Shou-Yen KaoDepartment of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Kai-Feng HungDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Omicron variant BA.2 is the dominant form of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in many countries, including those that have already implemented the strictest quarantine mandates that effectively contained the spread of the previous variants. Although many individuals were partially or fully vaccinated, confirmed Omicron infections have far surpassed all other variants combined in just a couple of months since the Omicron variant emerged. The ChAdOx1-S (AstraZeneca), BNT162b2 (Pfizer-BioNTech), and mRNA-1273 (Moderna) vaccines offer protection against the severe illness of SARS-CoV-2 infection; however, these currently available vaccines are less effective in terms of preventing Omicron infections. As a result, a booster dose of BNT162b2 or mRNA-1273 is recommended for individuals >12 years old who had received their second dose of the approved vaccines for >5 months. Herein, we review the studies that assessed the clinical benefits of the booster dose of vaccines against Omicron infections. We also analyzed public data to address whether early booster vaccination effectively prevented the surge of the Omicron infections. Finally, we discuss the consideration of a fourth dose of vaccine as a way to prevent possible upcoming infections.

Indexed as

2019-nCoV Vaccine mRNA-1273COVID-19BNT162 VaccineChildHumansSARS-CoV-22019-nCoV Vaccine mRNA-1273BNT162 Vaccine

Identifiers

PMID36524941
PMCPMC12755490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.