Evidence map›Paper›PMID 36524411›Full record

ArticleHistology and histopathology2023

Sex differences in vanadium inhalation effects in non-ciliated bronchiolar cells.

Nelly López-Valdez, Marcela Rojas-Lemus, Martha Patricia Bizarro-Nevares, Adriana Elizabeth González-Villalva, Martha Luz Ustarroz-Cano, Brenda Casarrubias-Tabarez, Gabriela Guerrero-Palomo, María Eugenia Cervantes-Valencia, Norma Rivera-Fernández, Teresa Imelda Fortoul

Abstract read
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In one paragraph

Article in Histology and histopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nelly López-ValdezCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Marcela Rojas-LemusCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Martha Patricia Bizarro-NevaresCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Adriana Elizabeth González-VillalvaCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Martha Luz Ustarroz-CanoCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Brenda Casarrubias-TabarezCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Gabriela Guerrero-PalomoGenomic Medicine and Environmental Toxicology Department, Biomedical Research Institute, National University of Mexico (UNAM), Ciudad de México, México.
María Eugenia Cervantes-ValenciaCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Norma Rivera-FernándezMicrobiology and Parasitology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México.
Teresa Imelda FortoulCellular and Tissular Biology Department, School of Medicine, National University of Mexico (UNAM), Ciudad de México, México. fortoul@unam.mx.
Universidad Nacional Autónoma de México · MXNational Institute of Genomic Medicine · MX

Funding

PAPIIT UNAM IN200418
6 · The paper itself

Abstract

The non-ciliated bronchiolar cell (NCBC) is responsible for the defense of the lung and responds to negative stimuli such as exposure to toxic pro-oxidant substances, which triggers the hyperproduction and hypersecretion of mucins and CC16 protein. The literature demonstrates that physiological and pathological responses in the lung can be influenced by the organism's sex. The objective of this report was to evaluate response differences to vanadium (V) inhalation in male and female CD-1 mice. Mice were exposed to V for four weeks. Hyperplasia of bronchiolar epithelium, small inflammatory foci and sloughing of the NCBC were observed, without changes between sexes and throughout the exposure time. Mucosecretory metaplasia was found in both males and females, however it was more drastic in males. The expression of CC16 increased in both sexes. This study demonstrated a different susceptibility between male and female mice exposed to V inhalation regarding mucosecretory metaplasia.

Indexed as

Sex CharacteristicsVanadiumAnimalsFemaleLungMaleMiceMice, Inbred StrainsRatsRats, Inbred F344Vanadium

Identifiers

PMID36524411
OpenAlexW4311663103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.