Evidence map›Paper›PMID 36524356›Full record

ArticleMolecular medicine reports2023

WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction.

Ida Marija Sola, Valentina Karin-Kujundzic, Frane Paic, Lada Lijovic, Mislav Glibo, Nikola Serman, Tihana Duic, Anita Skrtic, Krunoslav Kuna, Semir Vranic and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Decreased RSPO3 and β-Catenin in Preeclampsia: Correlation with Blood Pressure and Pregnancy Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ida Marija SolaDepartment of Obstetrics and Gynecology, University Hospital Sestre Milosrdnice, 10000 Zagreb, Croatia.
Valentina Karin-KujundzicDepartment of Biology, University of Zagreb, 10000 Zagreb, Croatia.
Frane PaicDepartment of Biology, University of Zagreb, 10000 Zagreb, Croatia.
Lada LijovicDepartment of Anesthesiology and Critical Care, General Hospital Fra Mihovil Sučić, 80101 Livno, Bosnia and Herzegovina, 10000 Zagreb, Croatia.
Mislav GliboDepartment of Biology, University of Zagreb, 10000 Zagreb, Croatia.
Nikola SermanZagreb Emergency Medicine Service; 6Department of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Tihana DuicDepartment of Biology, University of Zagreb, 10000 Zagreb, Croatia.
Anita SkrticCentre of Excellence in Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Krunoslav KunaDepartment of Obstetrics and Gynecology, University Hospital Sestre Milosrdnice, 10000 Zagreb, Croatia.
Semir VranicCollege of Medicine, QU Health, Qatar University, 2713 Doha, Qatar.
Ljiljana SermanDepartment of Biology, University of Zagreb, 10000 Zagreb, Croatia.
University of Zagreb · HRSisters of Charity Hospital · HRQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Placental insufficiency is a common cause of intrauterine growth restriction (IUGR). It affects ~10% of pregnancies and increases fetal and neonatal morbidity and mortality. Although Wnt and Hh pathways are crucial for embryonic development and placentation, their role in the pathology of IUGR is still not sufficiently explored. The present study analyzed the expression of positive regulators of the Wnt pathway, WNT5A and β‑catenin, and the expression of the Hh pathway negative regulator suppressor of fused (

Indexed as

beta CateninFetal Growth RetardationMicroRNAsWnt-5a ProteinEndothelial CellsFemaleHumansInfant, NewbornPlacentaPregnancyRepressor Proteinsbeta CateninCTNNB1 protein, humanMicroRNAsMIRN214 microRNA, humanMIRN378 microRNA, humanRepressor ProteinsSUFU protein, humanWnt-5a ProteinWNT5A protein, humanDNA methylationHh signaling pathwayintrauterine growth restrictionmicroRNA 214microRNA 378placentasuppressor of fusedWNT5AWnt signaling pathwayβ‑catenin

Identifiers

PMID36524356
PMCPMC9813565
OpenAlexW4312129947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.