Evidence map›Paper›PMID 36524254›Full record

Trial reportNeurorehabilitation and neural repair2023

Functional Neuroplasticity and Motor Skill Change Following Gross Motor Interventions for Children With Diplegic Cerebral Palsy.

Alicia J Hilderley, F Virginia Wright, Margot J Taylor, Joyce L Chen, Darcy Fehlings

3 registry-linked trialsOpen access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02584491 nacompletednot on this map

Linking Neuroplasticity With the Outcomes of Motor Learning Based Interventions: Multi-modal Evaluation of Walking-based Training in Children and Youth With Cerebral Palsy

TypeinterventionalSponsorHolland Bloorview Kids Rehabilitation HospitalRan2015 to 2016Enrolled9ConditionsCerebral PalsyArmsFunctional gait-related training
NCT02754128 nacompletednot on this map

Linking Neuroplasticity With the Outcomes of Walking-based Interventions: A Feasibility Trial Comparing a Motor Learning Versus a Strength-based Program in Children With Cerebral Palsy

TypeinterventionalSponsorHolland Bloorview Kids Rehabilitation HospitalRan2016 to 2017Enrolled20ConditionsCerebral PalsyArmsBeFAST, BeSTRONG
NCT06702709 nacompletednot on this mapstarted 2024, after this paper: background citation

EFFECTS of INSTRUMENT-ASSISTED SOFT TISSUE MOBILIZATION VS. NEURODEVELOPMENTAL THERAPY on MOTOR FUNCTION in CHILDREN with GMFCS LEVEL I and II SPASTIC DIPLEGIC CEREBRAL PALSY

TypeinterventionalSponsorZiauddin UniversityRan2024 to 2024Enrolled60ConditionsDiplegic Spastic Cerebral PalsyArmsInstrument Assisted Soft Tissue Mobilization, Neurodevelopmental Therapy
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alicia J HilderleyBloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada.ORCID 0000-0002-2462-0234
F Virginia WrightBloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada.
Margot J TaylorDiagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada.
Joyce L ChenFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Darcy FehlingsBloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada.
University of Toronto · CAHolland Bloorview Kids Rehabilitation Hospital · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGross motor intervention designs for children with diplegic cerebral palsy (DCP) require an improved understanding of the children's potential for neuroplasticity.

objectiveTo identify relations between functional neuroplasticity and motor skill changes following gross motor interventions for children with DCP.

methodsThere were 17 participants with DCP (ages 8-16 years; 6 females; Gross Motor Function Classification System Level I [n = 9] and II [n = 8]). Each completed a 6-week gross motor intervention program that was directed toward achievement of individualized motor/physical activity goals. Outcomes were assessed pre/post and 4 to 6 months post-intervention (follow-up). An active ankle dorsiflexion task was completed during functional magnetic resonance imaging. The ratio of motor cortical activation volume in each hemisphere was calculated using a laterality index. The

resultsChallenge scores improved post-intervention (4.57% points [SD 4.45],

conclusionsMotor cortical activation during non-dominant ankle dorsiflexion is a modest indicator of the potential for gross motor skill change. Further investigation of patterns of neuroplastic change will improve our understanding of effects. CLINICALTRIALS.GOV REGISTRY: NCT02584491 and NCT02754128.

Indexed as

Cerebral PalsyMotor SkillsAdolescentAnkleChildFemaleHumansWalkingcerebral palsyfunctional magnetic resonance imaginglower extremitymotor skillsneuroplasticity

Identifiers

PMID36524254
PMCPMC9896542
OpenAlexW4311671428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.