ArticleEpidemiology and infection2022
Estimation of the incubation period and generation time of SARS-CoV-2 Alpha and Delta variants from contact tracing data.
Article in Epidemiology and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessing changes in incubation period, serial interval, and generation time of SARS-CoV-2 variants of concern: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- Generation time in a discrete epidemic model with asymptomatic carriers: beyond geometric waiting times.Infectious Disease Modelling · 2027Article
- The impact of school-based mitigation measures on the transmission of respiratory pathogens: the case of SARS-CoV-2.International journal of epidemiology · 2026Article
- T-cell repertoire response in individuals with post-acute sequelae of COVID-19.bioRxiv : the preprint server for biology · 2026Article
- Estimating the effect of self-protection on transmission dynamics of SARS-CoV-2 in Germany in 2021: a modelling study.BMC public health · 2026Article
- Enhancing time-varying reproduction number estimates for COVID-19 with behavior and surveillance data in South Korea, 2020-2022.Archives of public health = Archives belges de sante publique · 2026Article
- Mitigating norovirus spread on cruise ships: a model-based assessment of diagnostic timing and isolation.Journal of travel medicine · 2025Article
- Identifying COVID-19 peaks using early warning signals.PLoS computational biology · 2025Article
- State-space modelling using wastewater virus and epidemiological data to estimate reported COVID-19 cases and the potential infection numbers.Journal of the Royal Society, Interface · 2025Article
- Modelling the effectiveness of antiviral treatment strategies to prevent household transmission of acute respiratory viruses.PLoS computational biology · 2024Article
- Generative Bayesian modeling to nowcast the effective reproduction number from line list data with missing symptom onset dates.PLoS computational biology · 2024Article
- Article
- Increasing situational awareness through nowcasting of the reproduction number.Frontiers in public health · 2024Article
- Machine Learning Algorithms Associate Case Numbers with SARS-CoV-2 Variants Rather Than with Impactful Mutations.Viruses · 2023Article
- Priority age targets for COVID-19 vaccination in Ethiopia under limited vaccine supply.Scientific reports · 2023Article
- Characterizing the role of human behavior in the effectiveness of contact-tracing applications.Frontiers in public health · 2023Article
- Tracking the progressive spread of the SARS-CoV-2 Omicron variant in Italy, December 2021 to January 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022Article
- Investigating the relationship between interventions, contact patterns, and SARS-CoV-2 transmissibility.Epidemics · 2022Article
- Designing isolation guidelines for COVID-19 patients with rapid antigen tests.Nature communications · 2022Article
- Intrinsic generation time of the SARS-CoV-2 Omicron variant: An observational study of household transmission.The Lancet regional health. Europe · 2022Article
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantitative information on epidemiological quantities such as the incubation period and generation time of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is scarce. We analysed a dataset collected during contact tracing activities in the province of Reggio Emilia, Italy, throughout 2021. We determined the distributions of the incubation period for the Alpha and Delta variants using information on negative polymerase chain reaction tests and the date of last exposure from 282 symptomatic cases. We estimated the distributions of the intrinsic generation time using a Bayesian inference approach applied to 9724 SARS-CoV-2 cases clustered in 3545 households where at least one secondary case was recorded. We estimated a mean incubation period of 4.9 days (95% credible intervals, CrI, 4.4-5.4) for Alpha and 4.5 days (95% CrI 4.0-5.0) for Delta. The intrinsic generation time was estimated to have a mean of 7.12 days (95% CrI 6.27-8.44) for Alpha and of 6.52 days (95% CrI 5.54-8.43) for Delta. The household serial interval was 2.43 days (95% CrI 2.29-2.58) for Alpha and 2.74 days (95% CrI 2.62-2.88) for Delta, and the estimated proportion of pre-symptomatic transmission was 48-51% for both variants. These results indicate limited differences in the incubation period and intrinsic generation time of SARS-CoV-2 variants Alpha and Delta compared to ancestral lineages.
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