Evidence map›Paper›PMID 36524210›Full record

Trial reportOncoimmunology2022

Immunological responses to adjuvant vaccination with combined CD1c

Martine Bloemendal, Kalijn F Bol, Steve Boudewijns, Mark A J Gorris, Johannes H W de Wilt, Sandra A J Croockewit, Michelle M van Rossum, Anna L de Goede, Katja Petry, Rutger H T Koornstra and 4 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Oncoimmunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Martine BloemendalDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.
Kalijn F BolDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0003-4165-2040
Steve BoudewijnsDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.
Mark A J GorrisDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0003-3621-226X
Johannes H W de WiltDepartment of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
Sandra A J CroockewitDepartment of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.
Michelle M van RossumDepartment of Dermatology, Radboud University Medical Center, Nijmegen, the Netherlands.
Anna L de GoedeDepartment of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
Katja PetryMiltenyi Biotec GmbH, Bergisch Gladbach, Germany.
Rutger H T KoornstraDepartment of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Carl FigdorDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.
Winald R GerritsenDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
Gerty SchreibeltDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.
I Jolanda M de VriesDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences; Radboud University Medical Center, Nijmegen, the Netherlands.
Radboud University Nijmegen · NLMiltenyi Biotec (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the immunological responses of lymph-node involved (stage III) melanoma patients to adjuvant dendritic cell vaccination with subsets of naturally occurring dendritic cells (nDCs). Fifteen patients with completely resected stage III melanoma were randomized to receive adjuvant dendritic cell vaccination with CD1c

Indexed as

Cancer VaccinesMelanomaAdjuvants, ImmunologicAntigens, CD1CD8-Positive T-LymphocytesCutaneous Malignant MelanomaDendritic CellsGlycoproteinsHumansVaccinationAdjuvants, ImmunologicAntigens, CD1Cancer VaccinesCD1C protein, humanGlycoproteinsclinical trialimmunotherapyMelanoma

Identifiers

PMID36524210
PMCPMC9746622
OpenAlexW4200452949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.