Evidence map›Paper›PMID 36524106›Full record

ArticleCurrent research in physiology2023

L-Arginine supplementation enhanced expression of glucose transporter (GLUT 1) in sickle cell anaemia subjects in the steady state.

W A Saka, C N Anigbogu, M O Kehinde, S I Jaja

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Article in Current research in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

W A SakaDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomosho, Nigeria.
C N AnigboguDepartment of Physiology, College of Medicine, University of Lagos, Lagos, Nigeria.
M O KehindeDepartment of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria.
S I JajaDepartment of Physiology, College of Medicine, University of Lagos, Lagos, Nigeria.
University of Lagos · NGLadoke Akintola University of Technology · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-Arginine may have therapeutic value in the management of sickle cell disease and diabetes mellitus. There is very little information on the interaction of GLUT 1 and L-Arginine in sickle cell disease subjects. This study compared the blood levels of Glut 1, fasting blood glucose (FBG) and fasting insulin (FIns) in non-sickle cell anaemia (HbAA) and sickle cell anaemia (HbSS) subjects in the steady state before and following L-Arginine supplementation (1 g/day for 6 weeks). Nitric oxide metabolites, (NO

Indexed as

CAT, CatalaseFasting blood glucoseFasting blood insulin levelFBG, Fasting blood glucoseFIns, Fasting blood insulinGLUT IGPx, Serum glutathione peroxidaseHbAA, Non-sickle cell anaemia subjectsHbSS, Sickle cell anaemia subjectsL-arginineMDA, Thiobarbituric acidNOx, Nitric oxide metabolitesSickle cell anaemiaSOD, Superoxide dismutase

Identifiers

PMID36524106
PMCPMC9747353
OpenAlexW4310736114

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.